Lumbrokinase Powder
Description
Lumbrokinase Powder – Premium Fibrinolytic Enzyme for Cardiovascular Health Solutions
Xi'an Le-Nutra Ingredients Inc offers pharmaceutical-grade Lumbrokinase Powder extracted through controlled fermentation of earthworm species. Our enzyme complex delivers ≥20000FU/g activity tested by fibrin plate method, manufactured in our 60,000㎡ GMP-certified facility with 3,000-ton annual capacity. This light yellow fine powder serves as a targeted fibrinolytic agent for nutraceutical formulators developing cardiovascular support products. With 14+ years of enzyme production expertise, we provide batch-traceable, compliance-ready ingredients supported by full documentation including FDA, ISO, Kosher certificates, maintaining 98% on-time delivery to global markets.

What Is Lumbrokinase Powder and Why It Matters?
The product is a multi-enzyme fibrinolytic complex derived from specifically bred earthworm species through advanced biotechnology processes. Unlike traditional anticoagulants, this enzyme directly degrades fibrin while activating plasminogen pathways.
The pharmaceutical industry values this ingredient for solving critical formulation challenges. Traditional thrombolytic agents often carry systemic bleeding risks and suffer from poor oral bioavailability. Our ingredient offers targeted fibrin breakdown with improved safety profiles for long-term supplementation.
Formulators appreciate its stability and concentrated activity. The enzyme complex maintains consistent performance across various delivery formats. This makes it suitable for capsule manufacturing, functional beverage development, and therapeutic food applications targeting microcirculation support.
Technical Specifications and Quality Parameters
| Item | Specification |
|---|---|
| Product Name | Lumbrokinase Powder |
| CAS Number | 556743-18-1 |
| Active Ingredient | Lumbrokinase Fibrinolytic Enzyme |
| Appearance | Light yellow free-flowing fine powder |
| Enzyme Activity | ≥20000FU/g (fibrin plate method) |
| Solubility | Easily soluble in warm purified water |
| Loss on Drying | ≤5.0% |
| Total Ash | ≤6.0% |
| Heavy Metals | Pb <10ppm, As <2ppm, Cd <1ppm, Hg <0.1ppm |
| Microbial Limits | TPC ≤1000CFU/g; Yeast & Mold ≤100CFU/g |
| Pathogen Testing | E. coli & Salmonella: Negative |
| Shelf Life | 24 months under proper storage conditions |
| Storage Conditions | Cool, dry, dark environment, sealed low-temperature |
Core Functions and Clinical Applications
Our enzyme complex supports multiple physiological pathways related to blood health. The fibrinolytic activity helps dissolve microthrombus formations that may impede proper circulation. This mechanism proves valuable in formulations targeting blood viscosity management.
The enzyme assists in maintaining comfortable microcirculation throughout peripheral tissues. Users developing products for limb numbness relief or circulation comfort find this property particularly useful. It works by supporting natural blood flow patterns without aggressive systemic effects.
Cardiovascular wellness formulations benefit from its auxiliary care properties. The ingredient complements daily heart health protocols by maintaining healthy blood states. This makes it suitable for preventive nutrition rather than acute intervention products.
Physical vitality support represents another application area. By promoting efficient nutrient delivery through improved microcirculation, the enzyme contributes to overall energy metabolism. Formulators incorporate it into vitality-boosting supplements and functional food matrices.
Manufacturing Excellence and Quality Assurance
Manufacturing plant We have six multifunctional processing lines for enzyme production. The controlled fermentation environment ensures reproducible enzyme activity between batches of output. Temperature controlled extraction maintains the fragile protein structures necessary for biological function.
Quality control begins with raw material verification. Our earthworm biomass is harvested from certified organic farms with proven breeding techniques. Each batch of arriving material is subject to microbiological screening and species confirmation before authorisation for processing.
Activity measurements are performed in our analytical laboratory utilising a standardised fibrin plate methodology. ICP-MS technology is employed for heavy metal testing with parts-per-million accuracy. Microbiological testing is performed according to USP procedures to verify safety for oral consumption use.
Complete traceability is provided through batch documentation. Every production lot is assigned a unique identification number, which links raw materials, processing settings and quality test results. This also helps to ensure you are meeting regulatory compliance in the many international markets where your items may be sold.

Formulation Versatility and Application Scenarios
This ingredient is used by product manufacturers in a variety of format categories. The most prevalent application is in hard capsule formulations, which are often dosed at 100-300mg per serving. The free flowing properties of Lumbrokinase Powder provide for good mixing and efficient encapsulation.
Drink mix producers add it to functional beverages to help with circulation. Its solubility in water at warm temperatures allows for its inclusion in beverage matrices. pH stability and co-ingredient interactions should be considered throughout formulation phases.
Adult nutrition solid drink powders are expanding market sectors. The enzyme works well in combination with complimentary botanicals such as ginkgo or hawthorn extracts. This creates synergistic formulations for complete vascular wellness programs.
For daily cardiovascular care, smaller concentrations are used for maintenance purposes of functional meals. Convenient delivery techniques are offered by soft chew formats and fortified snack products. These cater to people seeking proactive wellness solutions rather than therapeutic solutions.
Supply Chain Reliability and Global Service
This is our key ingredient and we retain safety supply for more than 30 days. This inventory strategy protects your manufacturing schedule against supplier disruptions. We work with certified earthworm farms to assure a consistent supply of raw materials for our products.
Flexible minimum order quantity supports new brands and established manufacturers Small-batch orders are treated with the same quality care as bulk contracts. This enables you to accelerate your product development cycles from initial trials to commercial scale-up.
We work with international logistics providers to ship to over 60 countries. We supply complete export documentation including health certifications, certificates of origin and phytosanitary documents. For large purchases we arrange sea freight and for urgent orders we arrange air express through our shipping staff.
Delivering ingredients is not the end of technical support. Our application scientists help you with formulation problems and stability optimisation. This collaborative strategy helps you succeed in product launches and remain competitive in the market.
Storage Guidelines and Handling Recommendations
Proper storage will sustain enzyme activity for the duration of the stated shelf life. Store in closed containers, away from temperatures above 25°C. Low moisture is important, since wet circumstances speed up enzyme breakdown.
When you open large containers, pour any unused amounts into smaller sealed containers. This minimises exposure to ambient air and moisture on repeated exposures. Desiccant packets serve to keep internal conditions inside storage tanks at their optimum.
Do not expose the powder to temperatures above 50°C during production activities. If possible, add the enzyme after heating for high temperature processing steps. This protects the protein structure and preserves the biological activity of the final products.
Light sensitive necessitates opaque container materials. Adequate protection is provided by amber glass or metallized film pouches. These factors prolong the shelf life of the product and ensure the consumer receives full strength formulations throughout the time of use.
FAQ
Q: What delivery timeframes should formulators expect?
A: In-stock orders ship within 3-5 business days after payment confirmation. Custom specifications requiring purity adjustments or activity modifications typically require 10-12 days production time. We communicate realistic timelines during quotation processes.
Q: How should production teams handle temperature sensitivity?
A: Avoid direct contact with high-temperature equipment during blending operations. When formulating products requiring heat processes, add the enzyme during cooling phases. This prevents thermal deactivation and preserves the intended biological activity.
Q: Which product formats work best for this enzyme?
A: Daily circulation support capsules represent the primary application. Nutritional supplements for adult wellness, vitality-boosting solid drinks, and functional foods targeting vascular care all utilize this ingredient successfully. Format selection depends on your target market preferences.
Q: Can this ingredient combine with anticoagulant formulations?
A: Due to its fibrinolytic properties, formulators should exercise caution when designing products for consumers taking blood-thinning medications. Product labeling should include appropriate usage warnings and healthcare provider consultation recommendations for at-risk populations.

Partner With Le-Nutra for Premium Enzyme Ingredients
Contact our ingredient specialists at enquiry@lenutra.com for Lumbrokinase Powder samples, technical datasheets, and customized quotations tailored to your project requirements.
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