5 HTP Powder
Description
5 HTP Powder | Premium 99% 5-Hydroxytryptophan for Mood & Sleep Formulations
Xi'an Le-Nutra Ingredients Inc delivers pharmaceutical-grade 5 HTP Powder extracted from African Griffonia simplicifolia seeds, achieving 99% purity verified by HPLC analysis. Our 60,000㎡ GMP-certified facility maintains 3,000 tons annual production capacity with 6 specialized extraction lines, ensuring batch consistency for global nutraceutical manufacturers. Each shipment includes complete COA documentation with heavy metal testing (Pb <0.5 ppm, As <1.0 ppm) and microbial analysis (TPC ≤250 CFU/g). Direct factory pricing eliminates intermediaries while maintaining 30-day safety stock for stable supply.
Technical Specifications of 5-Hydroxytryptophan
| Parameter | Standard |
|---|---|
| Active Ingredient | 5-Hydroxytryptophan (5-HTP) |
| Purity | 99% (HPLC) |
| CAS Number | 56-69-9 |
| Source | Griffonia Simplicifolia Seeds |
| Appearance | Off-white Crystalline Powder |
| Molecular Formula | C11H12N2O3 |
| Molecular Weight | 220.23 g/mol |
| Solubility | Water-soluble, Ethanol-soluble |
| Loss on Drying | ≤5.0% |
| Total Ash | ≤5.0% |
| Heavy Metals | Pb <0.5 ppm, As <1.0 ppm, Cd <1.0 ppm, Hg <0.1 ppm |
| Microbial Limits | TPC ≤250 CFU/g; E.coli & Salmonella: Negative |
| Shelf Life | 24 months (sealed, cool, dark storage) |
How 5 HTP Powder Works in Formulations
5 HTP Powder is the direct metabolic precursor between L-tryptophan and serotonin. It is unique in that it avoids the rate limiting enzyme tryptophan hydroxylase and crosses the blood brain barrier efficiently to increase serotonin levels in the central nervous system.
This technique takes care of three important formulation problems. First, it has higher bioavailability than ordinary L-tryptophan. Second, it offers quicker beginning of effect for mood stabilising formulations. Third, it provides a plant-based alternative to synthetic substances and satisfies customer need for natural support of nervous system health.
Our powder is easy to incorporate with co-factors such as Vitamin B6 and Magnesium for manufacturers producing multi-ingredient blends. Its particle size of 100 mesh can be uniformly mixed in high-speed tableting and encapsulation.
Core Functional Benefits for Product Development
Our pharmaceutical-grade ingredient has measurable benefits for your recipes. 99% purity standardisation allows for exact dose estimations for clinical strength goods.
The compound's natural capacity to increase serotonin synthesis is useful to mood management applications. It encourages in a natural way a balanced emotional reaction. Stress relief supplement manufacturers – get consistent outcomes from batch to batch.
Sleep support products work by using the serotonin to melatonin conversion route. This substance increases sleep onset and quality length. We have tested it to be stable against normal production stresses like heat and mechanical compression.
Appetite-controlling products use the satiety-promoting benefits of increased serotonin. It is related to emotional eating patterns in weight management formulas. The water-soluble profile also extends the new beverage applications.

Quality Assurance You Can Trust
Every production batch is tested in our ISO-certified labs in a multi-step process, which is quite strict. Raw ingredients are first screened for purity before entering extraction lines and are from certified African vendors.
Our HPLC testing, shows each batch of 5-Hydroxytryptophan is >99% 5-HTP with <.5% batch to batch fluctuation. Heavy metal panels are tested much beyond FDA guidelines and include a full panel of heavy metals including lead, arsenic, cadmium and mercury. Microbial screening consists of Total plate count, Yeast/mold, and confirmation of E.coli and Salmonella.
The 14+ years of activities in the production environment are GMP compliant. And our QC team conducts optical rotation testing (-30° to -35°) to confirm L-isomer purity. Full documentation including COA, TDS, MSDS and MOA are provided with every shipment.

Strategic Applications Across Industries
Nutraceutical firms create mood balance capsules, sleep aid tablets and stress relief softgels. The ingredient's compatibility with enteric coatings preserves it during gastrointestinal transit for targeted release.
Functional beverage developers make relaxing shots, cognitive recovery beverages. Our powder is stable at pH ranges 3.5-7.0 and withstands pasteurisation temperatures of up to 85°C for 15 seconds.
Brands in weight management are adding it to products that increase satiety and help to combat emotional eating. The natural origin helps support a clear label positioning and delivers measurable outcomes.
Clinical research centers use pharmaceutical grade material for serotonin related neurological research. Batch consistency guarantees reproducibility of research results during multi-year initiatives.

Flexible Cooperation Models
Direct access to the factory, bypassing the middleman markup and ensuring an uninterrupted supply. We have a flexible MOQ and the capacity of 3,000 tonnes per year to support the new brands and established distributors.

OEM/ODM services include formula optimisation, custom purity and private labelling. Our R&D team works together developing dosage forms from traditional tablets to novel delivery technologies. You get technical help across product lifecycle from inception to commercialisation.
The benefits of the supply chain include having 30 days of safety stock to cover numerous production cycles. We provide EXW, FOB, CFR, CIF, DAP, DDP terms with worldwide logistics partners covering North America, Europe and Southeast Asia markets. We accept T/T, Alibaba Trade Insurance, Western Union etc.
Packaging and Storage Solutions
Standard Packaging 25kg fibre drums with double-layer food-grade polyethylene bag inner liners. This structure is designed to protect the photosensitive chemical from light and oxidation during transport.
Custom packaging to fit your unique handling requirements. For smaller trial quantities, we send in sealed aluminium foil bag with nitrogen flushing. Intermediate bulk containers (IBCs) are useful for huge industrial orders in efficiently managing materials.
Store sealed containers in a cool dry place out of direct sunlight and away from heat. When stored properly, 99% potency is retained throughout the 24 month shelf life. We have extensive storage policies with technical bulletins for optimum storage of ingredients.
FAQ
Q: What is the principal use of this ingredient?
A: It is used in the manufacture of sleep-aid capsules, mood-stabilizing tablets, stress-relieving health products and appetite-controlling functional meals. It performs well in both solid dose forms and soluble beverage applications.
Q: How do you ensure raw material quality?
A: We procure natural Griffonia simplicifolia seeds from certified vendors in Africa. Each batch is tested for HPLC purity, including heavy metal analysis and microbiological screening. Every shipment has the full COA documentation traceable to source farms.
Q: What is the active ingredient and storage advice?
A: The main active ingredient is 5-Hydroxytryptophan standardised to 99% purity. The powder is light and oxidation sensitive thus store in a cold, dark, sealed environment at not more than 25 °C and not more than 60% RH.

Partner With Le-Nutra for Reliable Supply
Ready to elevate your formulations with pharmaceutical-grade 5 HTP Powder? Contact us at enquiry@lenutra.com for sample requests, technical specifications, or custom production inquiries.
Online Message
YOU MAY LIKE
High-quality Botanical Extracts, Functional Ingredients, And Nutraceutical Raw Materials Manufacturer And Supplier