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Naringenin Powder

Other Name: Naringenin powder CAS No: 480-41-1 Appearance: Off-white crystalline powder Specification: 98% Naringenin Detection Method: High Performance Liquid Chromatography (HPLC) Solubility: Soluble in ethanol, slightly soluble in hot water Functions: High-efficiency antioxidant, regulate lipid metabolism, relieve inflammatory response, protect liver, brighten skin and inhibit melanin Relevant Certifications: FDA, ISO, Kosher, COA, TDS, MSDS, MOA, etc. Delivery Terms: EXW, FOB, CFR, CIF, DAP, DDP Applications: Liver care supplements, lipid regulation functional foods, anti-inflammatory skincare raw materials, antioxidant oral health products Payment methods: 100% T/T; Alibaba International Trade Assurance orders; Western Union Packaging: 25 kg fiber drum, lined with a double-layer food grade polyethylene bags Storage: Keep in cool & dry place. Keep away from strong light and heat Shelf life: 24 months under the conditions above and in its original sealed packaging

Description

Naringenin Powder – High-Purity Citrus Flavanone for Nutraceutical & Cosmetic Applications

Xi'an Le-Nutra Ingredients Inc. is a professional supplier of Naringenin Powder pharmaceutical grade, 98% HPLC Verified. We produce in our 60,000㎡ GMP certified factory, and the production capacity is 3,000 tonnes annually. Our innovative enzymatic hydrolysis and recrystallisation process provides consistent off-white crystalline powder for lipid metabolism management, antioxidant skin care and liver protection formulations. With more than 14 years of extraction experience and 98% on-time delivery performance, we provide full compliance paperwork including FDA registration, ISO certification and batch-specific COA/TDS/MSDS reports for nutraceutical and cosmeceutical businesses worldwide.

Naringenin Powder

What Makes Our Naringenin Powder Different?

This substance is the bioactive aglycone form of naringin, produced by controlled hydrolysis of citrus peels. This crystalline powder has better lipophilicity and tissue penetration than glycoside precursors which have little absorption .

This flavanone tackles major industry issues. Manufacturers have challenges with variable plant extracts and inadequate bioavailability in conventional citrus powders. Our 98% pure ingredient avoids intestinal barriers, allowing for exact dosing in metabolic health supplements and anti-aging serums.

The chemical framework (C15H12O5) gives thermal stability up to 250°C allowing use in hot-fill processing and encapsulation technologies. The ethanol solubility is advantageous to liposomal delivery systems and transdermal cosmetic compositions.

Technical Specifications

Parameter Specification
Active Ingredient Naringenin (CAS 480-41-1)
Purity 98% min (HPLC)
Appearance Off-white crystalline powder
Source Citrus extract hydrolysis
Loss on Drying ≤0.5%
Total Ash ≤0.1%
Heavy Metals Pb <0.5 ppm, As <1.0 ppm
Microbial Limits TPC ≤250 CFU/g, E.coli/Salmonella negative
Solubility Soluble in ethanol, slightly in hot water
Shelf Life 24 months (sealed, cool, dark storage)

Core Benefits for Product Development

Five proven ways formulation scientists benefit from our high-purity powder First, the age-defense supplements have a DPPH radical scavenging capacity of about 92% to protect the cellular lipids from oxidative damage.

Second, clinical study shows that activation of PPARα lowers triglyceride buildup by 34% in lipid metabolism formulae. This mechanism enables weight control products that do not contain stimulating side effects.

Third, the substance at 50 μM concentration suppresses NF-κB inflammatory pathways. Skincare brands use this feature in redness-relief serums and sensitive skin treatments.

Fourth, tests on hepatocytes reveal a 28% decrease in the ALT enzyme, making it useful for tablets that protect the liver. Flavanone increases mitochondrial activity and glutathione synthesis.

Fifth, 0.5 mM tyrosinase suppression decreases the melanin biosynthesis by 41%. Brightening creams, dark spot correctors, this for visible tone improvement in 8 weeks

Naringenin Powder

Manufacturing Excellence

We use our own low temperature purification technique utilising enzymatic hydrolysis and triple recrystallisation. This technique retains the phenolic hydroxyl groups required for bioactivity and lowers naringin residues to below 0.3%.

Batch-to-batch uniformity is assured by six multi-functional production lines with chromatographic separation. During the 72-hour extraction cycle, real-time HPLC monitoring ensures the maintenance of purity requirements.

We have 23 point inspection processes in our quality control lab. These include FTIR spectroscopy for structure confirmation, Karl Fischer moisture analysis and ICP-MS heavy metal screening. 3rd party testing certification before release for every batch.

Temperature regulated warehousesStore at 15-20°C with nitrogen blanketing to prevent oxidation. This infrastructure supports our 30-day safety stock policy to ensure ongoing supply worldwide.

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Applications Across Industries

Naringenin Powder is used by nutraceutical producers in capsules to support cardiovascular health and cholesterol management. The usual dose is 250-500 mg per day, together with CoQ10 or bergamot extracts to provide a synergistic effect.

Cosmetic formulators utilise concentrations of 0.5-2% in anti-aging serums. It is a component that can be used in combination with vitamin E and ferulic acid in anhydrous solutions, so that hydrolysis does not occur in aqueous systems.

Functional food makers put it in meal replacement bars and metabolic support drinks. It also provides antioxidant fortification, in addition to its bitter masking qualities that accompany stevia sweeteners.

Pharmaceutical companies are exploring it to improve bioavailability. It inhibits CYP3A4 enzymes to increase the plasma half-life of poorly absorbed medicines and hence reduce dose frequency.

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Customization and Supply Solutions

As part of our OEM/ODM services, we provide micronization down to D50 <10 μm for improved dissolving rates. We also co-process with phospholipids to form self-emulsifying delivery systems.

We provide private labelling in bags from 1 kg foil bags up to 25 kg fibre drums with double food-grade polyethylene liners. Brand distinction through custom printing and multi-language documentation.

Flexible MOQ options for trial batches (minimum 5 kilogram) and bulk contracts of more than 500 kg/month. With our EXW, FOB and DDP terms, shipping internationally from Xi'an to your facilities is a breeze.

Payment terms: T/T transfers, Alibaba Trade Assurance, LC for established partners. We keep communication clear with a dedicated account manager speaking English, Spanish and German.

FAQ

Q: Where do you recommend using this ingredient?

A: It performs optimally in lipid balance capsules, liver detox tablets, anti-inflammatory facial serums, and antioxidant oral supplements. Stability testing confirms compatibility with most excipients except strong oxidizers.

Q: What makes your production process unique?

A: We utilize enzymatic hydrolysis combined with recrystallization at controlled sub-zero temperatures. This method achieves 98% purity while preserving the three critical hydroxyl groups at positions 4', 5, and 7 on the flavonoid backbone.

Q: How should formulators store this material?

A: The compound is photosensitive and prone to oxidation. Store in fully sealed containers below 25°C, away from direct light. Argon flushing extends stability in opened packages. Once incorporated into formulations, add tocopherols or BHT as stabilizers.

Q: Can you adjust specifications for specific applications?

A: Yes, our R&D team modifies particle size distribution, bulk density, and solvent residuals. We also produce naringenin-phospholipid complexes with 3-5x improved oral bioavailability for premium supplement lines.

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Partner With a Trusted Manufacturer

Ready to elevate your formulations with premium Naringenin Powder? Contact our ingredient specialists at enquiry@lenutra.com for samples, technical datasheets, and customized quotations tailored to your project requirements.

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