Acetyl Octapeptide 3 Powder
Description
Acetyl Octapeptide 3 Powder – Premium Anti-Wrinkle Peptide for Advanced Cosmetic Formulations
Xi'an Le-Nutra Ingredients Inc is professional manufacturer of top grade Acetyl Octapeptide 3 Powder with HPLC Purity ≥98.0%. We have a GMP-certified production facility of 60,000㎡ with an annual output capacity of 3,000 tonnes, providing a consistent bulk supply to worldwide cosmetic manufacturers. This is a sophisticated octapeptide that has been proven to have better anti-wrinkle efficacy than typical hexapeptides and has been shown to improve wrinkle depth reduction by roughly 30%. With over 14 years of experience in peptide synthesis and rigorous quality control systems, we offer a consistent white to off-white crystalline powder that meets international requirements for cosmetic ingredients, helping your high-end anti-aging product development.
What Is Acetyl Octapeptide 3 Powder and How Does It Work?
Commercially known as SNAP-8, the substance is an eight amino acid synthetic peptide designed for topical anti-wrinkle uses. The chemical works by imitating the N-terminal part of the SNAP-25 protein and so competes for binding to the SNARE complex that is involved in the release of neurotransmitters.
This neuromuscular communication route is modulated by the peptide to lessen the intensity of face muscle contraction, without invasive treatments. The molecular weight (1075.2 g/mol) allows for excellent penetration into the skin and stable bioactive properties.
The botox-like mechanism given through a safe topical treatment is an advantage to your products. In controlled research clinical observations have shown up to 63% reduction in wrinkle depth, making this substance a critical component of needle free anti-aging products for expression lines in the eye, forehead and mouth areas.
Technical Specifications and Quality Parameters
| Parameter | Specification |
|---|---|
| Product Name | Acetyl Octapeptide-3 |
| CAS Number | 868844-74-0 |
| Appearance | White to off-white crystalline powder |
| Assay | ≥98.0% (HPLC) |
| Molecular Weight | 1075.2 g/mol |
| pH (1% solution) | 5.0~7.0 |
| Loss on Drying | ≤0.5% |
| Melting Point | 190-195℃ |
| Heavy Metals | ≤10 ppm |
| Lead | ≤2 ppm |
| Arsenic | ≤2 ppm |
| Total Plate Count | ≤100 CFU/g |
| Yeast & Mold | ≤10 CFU/g |
| E. Coli | Negative |
| Salmonella | Negative |
| Shelf Life | 24 months (proper storage) |
Our rigorous testing protocols ensure each batch meets pharmaceutical-grade standards. Complete documentation including COA, TDS, and compliance certificates accompanies every shipment.
Core Anti-Aging Benefits for Cosmetic Applications
Better Wrinkle Reduction Performance
Octapeptide structure shows 2-3 times more anti-wrinkle effectiveness than hexapeptide alternatives. Your products show a visible reduction in dynamic expression lines in 28-day application cycles.
Inhibition of Muscle Contraction
The active substance prevents the formation of the SNARE complex and hence decreases the intensity of the face muscles' activity. This is what the process is targeting. It is the repetitive nature of some emotions that cause the ageing marks we see on the face, such as frown lines, crow's feet and forehead wrinkles.
Benefits of Skin Tightening and Firming
with addition to reducing wrinkles, skin suppleness is enhanced with formulations containing this peptide. This dual action works to soften lines immediately, while improving structure over the long-term.
Sensitive Skin Safety Profile
Topical therapy avoids the hazards of systemic exposure of injectable therapies. The gentle nature allows for daily use serums and creams with no worry of irritation, extending your target consumer base.

Formulation Guidelines and Application Recommendations
You need to add this ingredient in the cooling phase below 40℃ to retain the integrity of the peptide, thus your development team should do it. Typical concentration range is 3% to 10% based on the desired level of efficacy and product positioning.
The powder shows high solubility in water for easy incorporation into aqueous serum, gel and emulsion systems. It is stable at pH 5.0-7.0 which provides good compatibility with most cosmetic bases without the need for further buffering.
Synergistic combinations with hyaluronic acid, vitamin C derivatives and other anti-aging actives boost product performance overall. Think about combining with moisturisers to help support the skin barrier function, while providing anti-wrinkle benefits.
Higher doses mean more noticeable benefits, which is why premium eye creams and intense treatment serums use them. Moisturisers used daily have a moderate dose that is effective but cost effective for wider market appeal.

Storage Requirements and Handling Best Practices
Acetyl Octapeptide 3 Powder should be stored in sealed containers in a cool dry place away from direct light to maintain product integrity. Shelf life can be prolonged by preserving at 2-8℃ in refrigerator and long-term bioactivity can be preserved.
Controlling humidity limits the absorption of moisture that can affect powder flowability and potency. Once opened minimise exposure to air by resealing containers immediately after dispensing the needed quantities.
Temperature variations during shipment need to be addressed. We pack in 25 kg fibre drums with double layer food-grade polyethylene bags which give excellent protection suitable for international shipping routes.
Quality retention shelf life is 24 months if the above storage practices are followed. You turn over stock often so your production is working with best before dates.
Why Our Acetyl Octapeptide 3 Powder Stands Apart?
Advantage of Direct Factory Sourcing
We have integrated the production to avoid intermediate markups and to ensure supply consistency. You get competitive pricing without sacrificing the ≥98.0% purity requirement that's crucial for premium cosmetic applications.
Ability to Customise
Besides conventional specs, we can also provide private labelling, special package sizes and documentation to meet your regulatory requirements. OEM/ODM Services We cover the entire product lifecycle from concept to market launch.
Worldwide Compliance Support
Our quality management systems are compliant with GMP, ISO and FDA norms. All batches are tested for heavy metals and for microbiological contamination and purity verification with full traceability documentation.
Reliable Performance in the Supply Chain
30+ days safety stock and created logistical agreements to maintain 98% on-time delivery to North America, Europe and Asia-Pacific regions. MOQ is flexible, support both trial order and large quantity purchase.
FAQ
Q: What is the difference between Acetyl Octapeptide-3 and Acetyl Hexapeptide-8?
A: The octapeptide is a more advanced formulation with superior anti-wrinkle efficacy. With a longer peptide chain, it provides 2 to 3 times better action against deep expression lines, thereby justifying a premium placement. Hexapeptide-8 is an affordable alternative for typical anti-aging lines, whereas octapeptide-3 is aimed at demanding clients looking for the highest efficacy.
Q: What Concentration Should I Use In My Formulation?
A: Typically 3-10% depending on the product kind & market segment. Intensive treatment serums include higher concentrations for observable outcomes; everyday moisturisers balance efficacy with formulation economics.
Q: Can this ingredient be combined with other actives?
A: Yes, it shows great compatibility with complimentary anti-aging compounds. When combined with moisturising ingredients, antioxidants, and collagen stimulating compounds, we get all-encompassing skincare products that tackle several ageing factors at the same time.
Q: What temperature is preferred for incorporation?
A: Add during the cooling step under 40℃ to avoid thermal breakdown of peptide links. This temperature consideration maintains the bioactive structure required for neuromuscular modulation actions.

Partner With a Trusted Ingredients Supplier
Ready to elevate your anti-aging product line with Acetyl Octapeptide 3 Powder? Contact our team at enquiry@lenutra.com for samples, technical specifications, and partnership discussions tailored to your business requirements.
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