Ecdoine Powder – Premium Biofermentation-Derived Stress Protection Ingredient for Cosmetic and Nutraceutical Applications

Xi'an Le-Nutra Ingredients Inc. specializes in delivering high-purity Ecdoine Powder through advanced biological fermentation technology. Our facility spans 60,000㎡ with an annual production capacity of 3,000 tons, ensuring consistent supply for global cosmetic, personal care, and dietary supplement industries. With over 14 years of expertise in natural ingredients, we offer specifications of ≥98.0% and ≥99.0% purity, backed by ISO, GMP, Halal, and Kosher certifications. Our strict quality control protocols include HPLC content testing, heavy metal screening, and microbial examination, guaranteeing batch stability and regulatory compliance for international markets.

What is Ecdoine Powder and Why It Matters for Your Formulations?

Ecdoine, scientifically known as tetrahydropyrimidine (CAS 96702-03-3), is a naturally occurring extremolyte originally discovered in microorganisms thriving in extreme environmental conditions. This white to off-white crystalline powder functions as a biological stress protector at the cellular level.

Your formulations benefit from its unique mechanism of action. The compound forms a protective hydration shell around proteins and cell membranes, preventing structural damage from external stressors such as UV radiation, pollution, and temperature fluctuations.

For cosmetic manufacturers, this translates into multi-functional ingredient solutions. For nutraceutical developers, it offers novel positioning in the anti-aging and eye health segments. The water-soluble nature and neutral pH (5.0-7.0 in 1% solution) ensure seamless integration into various product matrices without formulation challenges.

Technical Specifications and Quality Parameters

Parameter	Specification
Product Name	Ectoine
CAS Number	96702-03-3
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥98.0% / ≥99.0%
Loss on Drying	≤0.5%
Melting Point	280-285℃
pH (1% solution)	5.0-7.0
Molecular Weight	142.16 g/mol
Heavy Metals	≤10 ppm
Lead	≤2 ppm
Arsenic	≤2 ppm
Cadmium	≤1 ppm
Mercury	≤0.1 ppm
Total Plate Count	≤100 CFU/g
Yeast & Mold	≤10 CFU/g
E. Coli	Negative
Salmonella	Negative
Staphylococcus Aureus	Negative
Storage Conditions	Sealed, cool, dry, and dark place
Shelf Life	24 months

Core Functional Benefits for Product Development

moisturize Moisturising & Water Retention Technology

The chemical stabilises water molecules at the level of the skin barrier to give long-lasting hydration. Your moisturising compositions are superior to traditional humectants. Clinical applications demonstrated a considerable improvement in the prevention of transepidermal water loss, making it a perfect ingredient for leave-on skin care products for dry skin and dehydrated skin disorders.

Mechanisms of Repair and Protection of Barriers

Preferential exclusion principles stabilise the cellular membrane. This prevents the breakdown of structural proteins and lipid bilayers. Your barrier repair products are more effective at treating weakened skin issues. This preventive function is especially useful in post-aesthetic treatment formulations during the fragile healing phase.

Soothing & Anti-Inflammatory Properties

Stress protein stabilisation modulates the inflammation cascade. You can add this chemical into your sensitive skin product lines to minimise redness, irritation, and reactivity Gentle nature makes it ideal for post-sun healing and reactive skin formulations where harsh actives would further sensitise.

Anti-Aging and Photoprotection Capabilities

The cellular defence against oxidative stress is to protect protein structure and cellular energy. When paired with standard antioxidants your anti-aging systems receive a synergistic boost. Anti-pollution and anti-blue light products have extra protective functions, apart from the usual filtering methods.

Formula Compatibility and Synergistic Combinations

Mix Ecdoine Powder with ceramides, panthenol and asiaticoside for repairing sensitive skin systems. This combination provides full barrier restoration acting through synergistic pathways targeting lipids, hydration and cellular regeneration.

Combine with ergothioneine, vitamin C derivatives and retinaldehyde in formulations for anti-aging and photoaging prevention. These relationships establish multi-pathway antioxidant systems, addressing both acute oxidative damage and chronic ageing processes.

Use with hyaluronic acid and sodium polyglutamate for products that deliver extensive moisturization. This trio addresses multi-layer hydration from surface film creation to deep dermal water binding, relieving persistent dryness concerns across all skin types.

Quality Assurance and Manufacturing Excellence

All the steps of our biological fermentation production are according to ISO 9001 and GMP. Rigorous HPLC content analysis, heavy metal screening, microbiological testing and skin irritation evaluation are performed for each production batch. All shipments are accompanied with full paperwork including COA, TDS and MSDS.

The green fermentation procedure alleviates any fears of animal derived substances or synthetic contamination. Your items are clean label positioned and are eligible for organic certification. Batch traceability systems provide total visibility over the supply chain from the raw culture materials to the final packaging.

Our quality control team holds 30 days of safety stock to ensure supply continuity. Your production schedules are safe against ingredient supply delays, with 98% on-time delivery rates and established logistics agreements.

certification

Application Scenarios Across Industries

Cosmetics and Personal Care Products

Sensitive skin care lines benefit from delicate but powerful protection Post-procedure recovery products aid healing without discomfort. Anti-pollution day creams create a cellular defence. Eye Care Formulations: Safe but powerful hydration for the delicate periorbital area. Moisturising techniques provide long-lasting benefits without heavy textures.

Nutraceuticals and Dietary Supplements Development

Cellular protection for retinal cells, oral eye health supplements. Anti-aging tablets offer systemic stress defence. Skin health formulas act from inside to support barrier function. Sports nutrition items are used to counteract oxidative stress generated by exercise.

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Packaging and Global Delivery

Standard packaging is in 25 kg fibre drums with double layer food grade polythene bag liners to protect from moisture and retain powder integrity. Custom packaging is offered for OEM/ODM projects requiring a specific quantity or branding.

We offer flexible delivery options such EXW, FOB, CFR, CIF, DAP and DDP as per your logistics requirements. Transaction security: T/T,Western Union,PayPal,Alibaba Assurance Account.

FAQ

Q: What is the stability of the product in different pH formulations?

A: The powder is stable in pH 4.0-8.0, which is the range of most cosmetic and oral formulations. It is recommended to perform stability testing in advance for extreme pH conditions below 3.0 or above 9.0 to verify the compatibility.

Q: What is the suggested concentration for best results?

A: The effective range for stress prevention and moisturising advantages in cosmetics is found to be 0.5 to 2.0 %. Formulations for sensitive skin may begin at 1.0%. Specific recommendations on doses are available for the nutraceutical applications according to the health claims.

Q: Can I mix the product with active chemicals like retinoids or acids?

A: Yes, it is very compatible with most active ingredients. It assists in buffering any possible discomfort that may be caused by stronger chemicals and is therefore an appropriate supporting ingredient in advanced treatment formulas.

Q: What documents are provided for regulatory compliance?

A: All the products have Certificate of Analysis (COA), Technical Data Sheet (TDS), Material Safety Data Sheet (MSDS) and applicable certifications for Halal, Kosher, Non-GMO and allergen declarations. Third party testing reports can be requested in addition to the ones above.

Q: How do you ensure consistent quality across different production batches?

A: We use standardised fermentation techniques, approved analytical methodologies and rigorous quality inspections to ensure consistency. All the batches are subjected to the same set of tests and acceptance criteria are based on stability studies. Statistical process controls monitor key factors during manufacturing.

team

Partner With a Reliable Ingredient Supplier

Ready to enhance your product formulations with premium Ecdoine Powder? Contact us at enquiry@lenutra.com for customized solutions tailored to your specific application requirements.