Syn-Ake

Syn-Ake Premium Anti-Wrinkle Peptide – Botox-Like Solution for Advanced Skincare Formulations

Xi'an Le-Nutra Ingredients Inc. is a pharmaceutical-grade Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) supplier with guarantyd purity ≥98.0%. We have 14+ years of peptide synthesis experience and a GMP-certified production facility of 60,000㎡. Our yearly capacity is 3,000 tonnes and we assure reliable supply all over the world, strictly in conformity with ISO, FDA and Halal requirements. Every batch is rigorously tested using HPLC, heavy metals screening (≤10 ppm) and microbiological control (<100 CFU/g) to guarantee consistent quality for cosmetic producers all over the world.

What Is Syn-Ake and How Does It Work?

It is a synthetic tripeptide that mimics Waglerin-1, a polypeptide in the venom of the Temple Viper. This biomimetic peptide reversibly antagonises the muscle nicotinic acetylcholine receptor. It binds to the epsilon subunit and blocks the attachment of acetylcholine, and so effectively suppresses neuromuscular contraction.

This chemical provides a non-invasive topical alternative to invasive botulinum toxin injections for the treatment of dynamic wrinkles. It has a molecular weight of 375.4 g/mol and provides good penetration into the skin which allows effective delivery of the active chemicals to the target areas. It has a strict localised, totally reversible muscle relaxing effect that makes it a safe choice for everyday long-term use in luxury skincare products.

Technical Specifications and Quality Parameters

Core Functional Benefits for Cosmetic Applications

Botox-Like Wrinkle Removal

​​​​​​​Clinically shown to visibly soften expression lines in 2-4 weeks with constant use. Long term use of 8-12 weeks significantly eliminates forehead lines, crow’s feet and glabellar wrinkles and prevents line deepening.

Enhanced Efficacy Compared to Hexapeptides

Syn-Ake has improved anti-wrinkle performance than traditional hexapeptide alternatives, making it a better value for mid-to-high end anti-aging product development.

Inhibition of Muscle Contraction

The active peptide blocks the neurotransmitter impulses that control the movements of the face muscles. It acts on the source of dynamic wrinkles, which are caused by the repetition of expressions.

Anti-Aging and Firming Benefits

It also helps to improve skin elasticity and suppleness and reduce wrinkles. It’s gentle enough to be safe on sensitive skin, yet strong enough to meet high standards.

Better Stability Profile

The chemical demonstrates high heat stability and is active in pH 3.0–5.5 ranges. This resilience in normal cosmetic compounding procedures allows formulation flexibility for a variety of product kinds.

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Diverse Application Scenarios Across Skincare Segments

Targeted Anti-Ageing Formulations

The peptide is incorporated into eye creams and forehead serums, targeting crow's feet and glabellar lines, with visible effects shown in 28-day therapy cycles.

Spa and Clinical Treatments by Professionals

High concentration instant lift masks and iontophoresis solutions use the chemical for fast absorption and immediate visible benefits, perfect for pre-event skin prep routines.

Multi-Peptide Synergy System

Cosmetic chemists will combine this peptide with filler peptides like Palmitoyl Pentapeptide-4 or with neurotransmitter blocking chemicals like Argireline. These elaborate formulas deliver multi-pathway methods to dermis remodelling in premium anti-aging concentrations.

Eye Care Solutions

The gentle but effective action reduces tiny wrinkles in the delicate periorbital area, without irritation or sensitivity reactions.

Why Choose Le-Nutra as Your Syn-Ake Supplier?

Pharmaceutical-Grade Manufacturing Standards

In our GMP compliance facility we use sophisticated HPLC testing to ensure every batch has a purity level of 98.0% or more. The overall quality control comprises the full traceability paperwork, heavy metal screening and microbial testing.

Scalable Production Capability

Six multi-purpose lines serve orders from sample quantities to huge commercial volumes. Our yearly capacity is 3,000 tonnes, and we can ensure a reliable supply for both new brands and established businesses.

Technical Support, Total

Our R&D team offers formulation recommendations, stability testing results and compatibility evaluations. We help you tweak specifications and recommend applications that match your product development objectives.

Compliance Documentation Worldwide

Full certification packages include COA, TDS, Allergen declarations, Non-GMO verification, Halal, Kosher, ISO and GMP certificates. We support third party testing requirements for international regulatory compliance.

Flexible Delivery Methods

We work with trusted logistics partners across North America, Europe and South East Asia to handle EXW, FOB, CFR, CIF, DAP and DDP terms. 98% on-time delivery rates are achieved with safety stock of more than 30 days.

FAQ

Q: How long does it take to see anti-wrinkle results?

A: Most users notice fading of dynamic lines after 2–4 weeks of consistent application. Long-term use over 8–12 weeks produces more prominent anti-wrinkle efficacy, significantly reducing expression lines and preventing further deepening.

Q: What makes this peptide different from hexapeptides?

A: While hexapeptides offer moderate wrinkle reduction, this ingredient provides stronger anti-wrinkle effects with a better cost-performance ratio. Its molecular structure allows superior transdermal penetration and receptor binding efficiency.

Q: Is it safe for sensitive skin formulations?

A: Yes. The reversible and localized mechanism ensures a high safety profile for long-term daily use. The mild nature makes it suitable for sensitive skin products without compromising efficacy.

Q: Can it be combined with other active ingredients?

A: Absolutely. It works synergistically with other peptides, hyaluronic acid, and antioxidants. Our technical team can provide compatibility data and formulation recommendations for complex multi-active systems.

Q: What is the recommended usage concentration?

A: Typical cosmetic formulations use concentrations between 2%–4% for optimal efficacy. Higher concentrations may be employed in professional treatments under appropriate guidance.

Packaging and Order Information

Ready to enhance your anti-aging product line with Syn-Ake? Contact our technical team at enquiry@lenutra.com for samples, specification sheets, and customized formulation support.