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Deoxyarbutin Powder

Other Names: Deoxy Arbutin, 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol CAS Number: 53936-56-4 Appearance: White to off-white crystalline powder Specification: ≥99.0% tested by HPLC Core Functions: High-efficiency whitening & spot fading, inhibit tyrosinase activity, brighten skin tone, fade spots and acne marks, stronger whitening effect than ordinary arbutin Main Applications: High-end whitening skincare, spot fading serums, brightening creams, masks and other cosmetic formulations Packaging: 25 kg fiber drum, lined with double-layer food-grade polyethylene bags Certificates: COA, TDS, Allergen, Non-GMO, Halal, Kosher, ISO, GMP. Delivery Terms: EXW, FOB, CFR, CIF, DAP, DDP Payment Method: T/T, Western Union, Pay Pal, Alibaba Assurance Account 10 years experience on natural ingredients industry.

Description

Deoxyarbutin Powder – Premium Whitening Ingredient for Advanced Cosmetic Formulations

Xi'an Le-Nutra Ingredients Inc. is a manufacturer of pharmaceutical quality Deoxyarbutin Powder, a next generation tyrosinase inhibitor with purity ≥99.0 % validated by HPLC. Supported by our 60,000㎡ GMP-certified manufacturing facility and 3,000-ton annual capacity in 6 multipurpose production lines, we offer stable supply options for high-end skincare producers across the world. Our product (CAS 53936-56-4) is 10x better at whitening than traditional β-arbutin, with minimal irritation profiles, addressing important formulation issues in brightening serums, spot fade treatments, and anti-aging cosmetics. With more than 14 years of extraction experience and 98% on-time delivery rate, we offer direct factory pricing and complete compliance documentation, including COA, Allergen declarations, Halal, Kosher, ISO and GMP certifications.

What Makes Our Deoxyarbutin Powder Superior for Cosmetic Applications?

This substance is the most advanced arbutin derivative developed for professional skin care formulations. By removal of one hydroxyl group from the β-arbutin molecular architecture, the bioengineered compound exhibits significantly improved transdermal penetration and tyrosinase-binding affinity.

In your compositions, you benefit from its dual-action mechanism. On a cellular level, this substance competitively occupies tyrosinase active sites, preventing melanin manufacturing pathways prior to pigmentation. At the same time, it speeds up the metabolism of existing melanin deposits through increased cellular turnover mechanisms.

Our powder, unlike the alternatives based on hydroquinone, has very good safety profiles and is not cytotoxic. Phototoxicity investigations in clinical compatibility have not shown phototoxicity after UV exposure. Low irritation risk even at high dosages. It is therefore perfect for delicate skin formulations and long-term whitening treatments.

The crystalline powder form addresses typical liquid ingredient issues. You remove the worry of oxidation instability, hazards of microbiological contamination, and complex cold chain logistics of liquid actives.

Technical Specifications and Quality Parameters

Parameter Specification
Product Name Deoxyarbutin (Deoxy Arbutin)
CAS Number 53936-56-4
Appearance White to off-white crystalline powder
Assay (HPLC) ≥99.0%
Loss on Drying ≤0.5%
Melting Point 86-89℃
pH (1% solution) 5.0-7.0
Molecular Weight 194.23 g/mol
Heavy Metals ≤10 ppm
Lead (Pb) ≤2 ppm
Arsenic (As) ≤2 ppm
Total Plate Count ≤100 CFU/g
E. Coli Negative
Salmonella Negative
Storage Conditions Sealed, cool, dry, dark place
Shelf Life 24 months

Core Functional Advantages for Your Formulations

Your product creation obtains several competitive advantages using our ingredient. Potent inhibition of tyrosinase effectivelyWhitens the powder, tackling hyperpigmentation at the source (enzymes) rather than camouflaging it on the surface.

Brightening effects for a variety of skin tone issues. It is designed to treat age spots, post-inflammatory hyperpigmentation from acne scars, melasma patches, and uneven complexion problems that regular ingredients cannot treat.

The improved molecular framework gives a more powerful whitening effect than regular arbutin, while yet being mild. You can create powerful therapy formulations without the irritation walls that restrict traditional brightening actives.

Formulation compatibility is compatible with several cosmetic systems. Deoxyarbutin Powder is readily incorporated into emulsion creams, gel serums, and sheet mask essences and anhydrous oil bases without any precipitation or colour shifting problems.

Strategic Applications Across Cosmetic Categories

skin whiteningThis active is mainly useful for premium whitening skincare products. Your spot-correcting serums offer clinical-grade efficacy that warrants luxury positioning and premium pricing methods for competitive markets.

So that the management of melanin can continue during the sun exposure times, the powder is integrated into brightening day creams. The photostability of the substance ensures that it will work the same way with no deterioration under UV radiation.

Nite repair treatments take advantage of its increased melanin metabolism characteristics during the skin's natural regeneration cycles. Mature skin formulations blend it with peptides and retinoids for all-around anti-aging remedies.

Sheet masks and nighttime sleeping packs provide concentrated doses for demanding treatment regimes. The powder has exceptional solubility in aqueous environments, allowing high-load formulations to be achieved without compromising texture.

Manufacturing Excellence and Supply Reliability

You are paying the raw material cost plus the middleman markup. Our direct manufacturing approach eliminates the middleman markups. You get manufacturer pricing with full batch traceability and quality documentation for global regulatory submissions.

Production scale allows development stage sampling and commercial volume orders. Our multifunctional lines are able to process unique specs such as particle size modifications, co-processing with synergistic actives and private labelling services.

Quality assurance is built on strict GMP processes and testing on three levels. The incoming raw materials are checked, in-process checks and final product analysis are performed to verify each batch fulfils the required pharmacopeial standards prior to distribution.

Global logistics infrastructure ensures that products remain intact during international transit. For delicate climate zones we use pharmaceutical grade packaging with moisture barrier and temperature monitoring.

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Comprehensive OEM/ODM Customization Services

Full service customisation capabilities to bring your brand vision to life. Whitening complex optimisation is a team effort between formula development teams to achieve cost targets while providing efficacy by adjusting concentration ratios.

Specification modification is to comply with regional regulatory standards. We can adapt purity grades, particle sizes and analytical testing protocols to the standards of the destination market in North America, Europe and Asia-Pacific regions.

Packaging options range from bulk pharmaceutical drums to retail ready consumer packaging. Integrate your branding through private labelling, custom printing and special closure systems that improve user satisfaction.

Providing ingredients is not the end of application support. Our technical advisors offer formulation troubleshooting, stability testing guidance and claim substantiation data to help you get your products to market faster.

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FAQ

Q: How does Deoxyarbutin compare to alpha-arbutin in terms of whitening efficacy?

A: The tyrosinase inhibitory potency of deoxyarbutin is about 10 times that of β-arbutin, and has been shown in clinical tests to be much better than α-arbutin. The structural change improves cellular absorption and enzyme binding affinity, which results in noticeable outcomes in reduced treatment durations.

Q: What is the suggested concentration for use in cosmetic formulations?

A: Daily use products such as moisturisers and cleansers generally have a 1-3% concentration in professional formulations. For spot correction you can go up to 3-5% in intensive treatment serums. Always test the stability and compatibility of your total formula system.

Q: Does this substance photosensitise or does it include sunscreen warnings?

A: No, photosensitivity does not increase with this product. This chemical is also stable in sunshine, unlike certain whitening agents that become unstable with UV exposure. But when combined with a broad-spectrum SPF, it prevents the creation of new melanin, which maximises the whitening results.

Q: Can I use it with other active compounds such as vitamin C or niacinamide?

A: Yes, it exhibits excellent compatibility with most cosmetic actives. When combined with Vitamin C, antioxidant protection is increased and when combined with Niacinamide, several pigmentation pathways are targeted. Keep pH within 5.0-7.0 for best stability in multi-active compositions.

Q: What documentation do you supply for the international cosmetic registration?

A: We provide full regulatory support such as Certificate of Analysis, Allergen Declaration, Heavy Metal Test Reports, Microbial Analysis, Non-GMO Statement, Halal and Kosher Certifications, ISO and GMP Certificates and MSDS documentation for customs clearance and product registration purpose.

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Partner With Us for Your Whitening Product Innovation

Contact our technical team at enquiry@lenutra.com to request samples, discuss custom specifications, or explore how our Deoxyarbutin Powder elevates your cosmetic portfolio in competitive global markets.

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