Bosein Powder
Description
Bosein Powder – Premium Anti-Aging Active Ingredient for Advanced Skincare Formulations
Xi'an Le-Nutra Ingredients Inc. offers high quality Bosein Powder (Hydroxypropyl Tetrahydropyrantriol, CAS 439685-79-7) with a minimum assay of 98% made in our 60,000㎡ GMP certified production plant. We have over 14 years experience in natural ingredient development and produce up to 3,000 tonnes a year on 6 multi-purpose plants. This white crystalline powder has proven full layer anti-aging effects by boosting glycosaminoglycan (GAG) synthesis and stimulating collagen creation at the dermal-epidermal junction. Our direct factory supply approach cuts out the middle man benefiting cosmetic manufacturers and brand formulators with reasonable prices, consistent quality and 98% on-time global delivery.

What Is Bosein Powder and Why It Matters for Your Formulations?
Known in the skincare world as Pro-Xylane, Bosein is a breakthrough anti-aging active particularly formulated to target structural skin ageing at the cellular level. This bioactive molecule penetrates deep into the dermal-epidermal junction to rebuild the extracellular matrix, unlike topical moisturisers.
Your formulations will profit from the dual-action of its mechanism. It also speeds up the manufacture of glycosaminoglycan, which keeps the dermis hydrated and structurally sound. It also encourages fibroblasts to produce more collagen, which directly targets fine lines, sagging and loss of suppleness.
The chemical is very gentle and is excellent for delicate skin formulations where retinoids or strong acids can cause discomfort. This flexibility provides the possibility to formulate high-end anti-aging medicines, barrier repair serums and firming treatments while maintaining safety profiles.
Technical Specifications and Quality Parameters
| Parameter | Specification |
|---|---|
| Product Name | Bosein Powder |
| Other Names | Hydroxypropyl Tetrahydropyrantriol, Pro-Xylane |
| CAS Number | 439685-79-7 |
| Appearance | White to off-white crystalline powder |
| Assay | ≥98.0% (HPLC) |
| Molecular Weight | 192.21 g/mol |
| Loss on Drying | ≤0.5% |
| Melting Point | 85-92℃ |
| pH (1% solution) | 5.0~7.0 |
| Heavy Metals | ≤10 ppm |
| Lead | ≤2 ppm |
| Arsenic | ≤2 ppm |
| Total Plate Count | ≤100 CFU/g |
| Yeast & Mold | ≤10 CFU/g |
| E. Coli | Negative |
| Salmonella | Negative |
| Storage | Sealed, cool, dry, dark place |
| Shelf Life | 24 months |
Core Functional Benefits for Cosmetic Applications
Promotes the Synthesis of Glycosaminoglycans
The chemical directly promotes the GAG synthesis in the dermis. It maintains the skin’s natural moisture-binding ability and strengthens the structural support of the upper epidermal layers.
Enhances Collagen Production
It stimulates fibroblast metabolism, leading to increased synthesis of Type I and Type VII collagen. This strengthens the dermal-epidermal junction, leading to a reduction in wrinkle depth and an increase in skin suppleness.
Repairs & Strengthens Skin Barrier
Bosein Powder improves the barrier function by optimising the structure of lipids and increasing ceramide synthesis. Your barrier repair products have a proven ability to restore weakened skin.
Delivers Visible Firming and Line Reduction
Clinical trials show noticeable changes in elasticity and fine line appearance within 8-12 weeks of constant use at prescribed doses.
Gentle Enough for Sensitive Formulations
This ingredient provides anti-aging benefits without irritation, unlike harsh exfoliants or high strength actives, and is perfect for products for rosacea prone or reactive skin.
Versatile Application Scenarios Across Product Categories
This active ingredient can be used in several skincare formulations. It is used at quantities of 2-3% for its potency in premium anti-aging serums. In eye creams it is used for its gentle but powerful wrinkle-reducing qualities within the delicate periorbital area.
It is used in barrier repair formulations to heal weakened skin after chemical peels or environmental damage. This is used in body firming creams to combat loss of elasticity in décolletage and arm areas. Used as a major active in anti-aging masks to give intensive therapy results.
Its stability in emulsion systems means it can be used in both water-based and anhydrous formulations, allowing you formulation versatility across your product line.

Professional Manufacturing and Quality Assurance
Our production facility of 60,000㎡ is in strict compliance with GMP and ISO quality management system. Prior to release, each batch is tested for HPLC assay verification, heavy metal screening, microbiological analysis and a number of other tests.
We keep over 30 days of safety stock on hand to keep your production schedules running. Our experienced QC team offers full batch traceability and support for third-party testing needs to ensure regulatory compliance in worldwide markets.
In the production process, modern synthesis and purification technologies are used to ensure consistent ≥98% purity. Our expert R&D team can customise specifications and give technical support for formulation optimisation.

Storage Recommendations and Usage Guidelines
Store in airtight containers, protected from light, heat and moisture. Storage: below 25℃, relative humidity less than 60%, best conditions.
In formulating, add the ingredient in the chilling process below 45°C to maintain bioactivity. High heat can destroy the chemical and limit efficacy. It synergistically works with hyaluronic acid, peptides, niacinamide and ceramides for added anti-aging benefits.
In leave-on products use levels are recommended to be 1-3% with greater levels delivering more noticeable results. You should always do stability testing in your formulation matrix.
Packaging and Global Delivery
Standard Packaging: 25 kg fibre drum with double layer food grade polyethylene inner bags to maintain product integrity during international shipping.
We can supply goods on different Incoterms – EXW, FOB, CFR, CIF, DAP, DDP – as you like. 1. Payment terms: T/T, Western Union, Paypal, Alibaba Trade Assurance for safe payment.
We have created logistics agreements which offer us with reliable sea freight, air freight and express courier services to North America, Europe, South East Asia and other parts of the world. With 98% on-time delivery performance you may arrange production with confidence based on our supply commitments.
FAQ
Q: What is the product's water solubility for aqueous formulations?
A: Bosein is well soluble in water up to 5% concentration in neutral to slightly acidic pH ranges. For greater concentrations apply suitable solubilizers or add during Emulsification stage in cream bases.
Q: How do you verify that the purity is consistent from batch to batch?
A: We do quantitative analysis by HPLC for each batch against verified reference standards. Our quality system has tight process controls and we provide a Certificate of Analysis with each shipment attesting to purity, heavy metals and microbiological safety.
Q: Can I use the product alongside other active ingredients like retinol or vitamin C in my formulations?
A: Yes, Bosein is very compatible with most active ingredients in cosmetics. It does not create antagonistic interactions like certain acids or retinoids do. However, always test for stability in your full formulation to ensure compatibility over your desired shelf life.
Q: What type of packing do you use for large orders ?
A: Standard packing is 25kg fibre drums with double layer food grade polyethylene bags. For larger purchases, we can custom pack in smaller subdivision containers or particular labelling for your manufacturing needs.
Q: Is the powder sensitive to specific handling in the formulation?
A: The powder is hygroscopic thus avoid exposure to air when weighing and handling. Use clean, dry equipment and integrate into compositions shortly after opening. Normal lab PPE is all that is needed for safety; no extra safety equipment is necessary. Normal cosmetic production techniques are sufficient.

Partner With a Trusted Ingredient Supplier
Ready to enhance your skincare formulations with premium-grade Bosein Powder? Contact us at enquiry@lenutra.com to request technical data sheets, sample quantities, or discuss your specific formulation requirements.
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