Acetyl Tetrapeptide-5 Powder

Acetyl Tetrapeptide-5 Powder | Professional Eye Care Peptide Solution for Anti-Puffiness and Dark Circle Reduction

Acetyl Tetrapeptide-5 Powder (≥98.0% HPLC) from Xi'an Le-Nutra Ingredients Inc is a high purity product for cosmeceutical producers seeking for a powerful answer to periorbital care. With our state-of-the-art 60,000㎡ GMP-certified production facility, 3,000 tonnes yearly production capacity and high quality standards, we give consistent quality solution to key industry concerns such as localised fluid retention, capillary permeability and glycation-induced elasticity loss. With over 14 years of peptide synthesis experience, we guarantee a reliable supply and 98% on time delivery, supporting your formulation development with complete technical documentation including COA, TDS and regulatory compliance certificates. This speciality eye care active peptide combines anti-puffiness, dark circle reduction and fine line improvement into one potent ingredient.

Advanced Biochemical Properties and Technical Specifications

The tetrapeptide (Ac-beta-Ala-His-Ser-His-OH), CAS Number 820959-17-9, with a molecular weight of 492.5 g/mol, possesses a molecular conformation that enhances its water solubility in cold-process formulations. What we utilise is an Angiotensin-Converting Enzyme (ACE) inhibitor. It targets the core cause of vascular permeability and fluid retention, not the transitory vasoconstriction that typical caffeine-based therapies offer.

The white to off-white crystalline powder is stable over the pH range of 5.0-7.0, therefore offering compatibility with a variety of cosmetic actives and rheology modifiers. Our tight manufacturing controls guarantee loss on drying ≤0.5% and heavy metals ≤10 ppm, in accordance with worldwide cosmeceutical standards.

Triple-Action Mechanism for Complete Periorbital Rejuvenation

Your formulation issues require chemicals that solve several problems at the same time. This specific peptide provides three clinically-relevant effects through independent biological routes.

Anti-Puffiness Action: Prevents periorbital oedema by blocking ACE activity, therefore reducing vascular permeability and stopping the buildup of fluid. Puffiness is noticeably reduced in 1-2 hours after application, with additional improvements following prolonged use.

Dark Circle Reduction: The substance stimulates local microcirculation and favours lymphatic drainage. This addresses the build-up of haemoglobin breakdown products that create blue-red pigmentation that topical concealers can't treat.

Anti-Glycation & Fine Line Reduction: It combats collagen cross-linking that leads to loss of suppleness and sagging. Its anti-glycation activity makes it particularly suitable for use in formulations targeting mature skin when the structural integrity is weakened.

Formulation Integration and Compatibility Guidelines

Your R&D team will love the adaptability of Acetyl Tetrapeptide-5 Powder in different cosmeceutical matrices. Its water solubility makes it suitable for use in aqueous serums, gel creams, hydrogel eye patches and emulsion based eye creams.

To optimise bioactivity retention chill the powder at <40℃ during the cooling step of your production process. It is well compatible with other common eye care actives such as hyaluronic acid, vitamin C derivatives, niacinamide and caffeine.

Depending on the desired efficacy level and product placement, the recommended use concentration is between 0.5% and 3.0%. If properly kept, the substance is stable in anhydrous and aqueous systems.

Quality Assurance and Regulatory Compliance

All production batches are extensively tested in our modern analytical laboratory. Full paperwork including Certificate of Analysis, Technical Data Sheet, Allergen Statement, Non-GMO certification and microbiological test results are provided.

We produce using GMP, ISO and FDA compliant quality standards with complete batch traceability. Heavy metal screening (lead, arsenic, cadmium and mercury) is substantially below the international levels. Microbial testing revealed no E. Coli, Salmonella or Staphylococcus Aureus.

Third-party testing help for your market needs in North America, Europe and Asia-Pacific.

Flexible Supply Solutions and Professional Support

We know your production schedule depends on dependable sourcing partners. Our 30-day safety stock system guarantees constant availability and customisable MOQ options for trial batches or commercial scale.

The product is packed in 25 kg fibre drums lined with double layer food grade polyethylene to preserve the product integrity for overseas delivery. For your convenience in logistics planning, we offer many delivery terms: EXW, FOB, CFR, CIF, DAP and DDP.

For your convenience, we accept T/T, Western Union, PayPal and Alibaba Trade Assurance.

FAQ

Q: What makes Acetyl Tetrapeptide-5 superior to caffeine for eye puffiness?

A: Caffeine causes a temporary constriction of blood vessels, but this peptide treats the root cause by suppressing ACE activity and reducing vascular permeability. This provides both immediate and cumulative long term effects that simple vasoconstrictors cannot provide.

Q: How should you store the powder for best potency?

A: Keep in sealed containers in a cool, dry, dark place away from intense light and high temperatures. Recommended storage temperature: refrigerated 2-8℃ Shelf life: 24 months Always protect from moisture as it is hygroscopic.

Q: What results can your customers expect from formulations containing this ingredient?

A: The immediate result is evident reduction of puffiness which can be noticed in 1-2 hours after application. With continued use for 2-4 weeks, users see dramatic improvement in dark circles and fine wrinkles. Improved skin elasticity around the sensitive eye area with cumulative effects from long-term usage.

Q: Is this substance safe for the delicate eye area?

A: Yes, the high level of purity (≥98.0%) minimises the possibility of peptide impurities that may lead to irritation or immunogenic reactions. It has a gentle biochemical effect, which is suitable for the delicate periorbital area, where the skin is the thinnest and most reactive.

Partner With a Reliable Peptide Supplier

Transform your eye care product line with pharmaceutical-grade Acetyl Tetrapeptide-5 Powder from Xi'an Le-Nutra Ingredients Inc. Contact us at enquiry@lenutra.com for samples, technical documentation, or custom specification inquiries.