thumbnail-image-0
thumbnail-image-0

Epitalon Powder

Other Names: Epithalon, Epithalamin, Ala-Glu-Asp-Gly Tetrapeptide CAS Number: 307297-39-8 Appearance: White to off-white crystalline powder Specification: ≥98.0% Core Functions: Telomere repair, cellular senescence delay, cell activation & repair, circadian rhythm regulation, anti-oxidation Main Applications: High-end anti-aging skincare, dietary supplements, anti-aging health products, cell repair formulations Packaging: 25 kg fiber drum, lined with double-layer food-grade polyethylene bags Certificates: COA, TDS, Allergen, Non-GMO, Halal, Kosher, ISO, GMP. Delivery Terms: EXW, FOB, CFR, CIF, DAP, DDP Payment Method: T/T, Western Union, Pay Pal, Alibaba Assurance Account 10 years experience on natural ingredients industry.

Description

Epitalon Powder for Advanced Anti-Aging Solutions – Pharmaceutical Grade Tetrapeptide with Telomere Repair Technology

Xi'an Le-Nutra Ingredients Inc. supplies premium Epitalon Powder, a pharmaceutical-grade tetrapeptide (Ala-Glu-Asp-Gly) engineered for advanced anti-aging applications. Our product maintains ≥98.0% purity verified by HPLC, manufactured in a 60,000㎡ GMP-certified facility with 3,000 tons annual production capacity. This bioactive ingredient addresses cellular senescence through telomere repair mechanisms, providing reliable raw material solutions for high-end skincare formulations, dietary supplements, and regenerative health products. With 14+ years of peptide extraction expertise and strict quality control following ISO, FDA, and GMP standards, we deliver batch-consistent product that meets global regulatory requirements for nutraceutical and cosmetic industries.

Understanding Epitalon Powder: Bioactive Tetrapeptide Technology

The product represents a sophisticated class of short-chain peptides specifically designed for cellular rejuvenation. Unlike conventional anti-aging compounds, this tetrapeptide operates at the chromosomal level by activating telomerase enzyme activity. Telomeres naturally shorten with each cell division, eventually triggering cellular senescence.

This powder delivers concentrated peptide sequences that counteract this degradation process. The molecular structure enables effective penetration through cellular membranes, reaching nuclear compartments where chromosomal repair occurs. Manufactured through solid-phase peptide synthesis with rigorous purification protocols, our product achieves pharmaceutical-grade quality suitable for clinical-level formulations.

The white to off-white crystalline appearance indicates high purity, while the stable powder form solves logistical challenges associated with liquid peptide storage. This format ensures extended shelf life, simplified transportation, and precise dosing in manufacturing environments.

Technical Specifications

Parameter Specification
Product Name Epitalon
CAS Number 307297-39-8
Appearance White to off-white crystalline powder
Assay ≥98.0% (HPLC)
Loss on Drying ≤0.5%
Melting Point 220-225℃
pH (1% solution) 5.0~7.0
Molecular Weight 390.38 g/mol
Heavy Metals ≤10 ppm
Lead (Pb) ≤2 ppm
Arsenic (As) ≤2 ppm
Cadmium (Cd) ≤1 ppm
Mercury (Hg) ≤0.1 ppm
Endotoxin ≤0.1 EU/mg
Total Plate Count ≤100 CFU/g
Yeast & Mold ≤10 CFU/g
E. Coli Negative
Salmonella Negative
Storage Sealed, cool, dry, dark place; refrigeration recommended
Shelf Life 24 months

Five Core Functional Advantages

Telomere Repair Mechanism

The big sell is that it can help to promote synthesis of telomerase, the enzyme that keeps telomeres at a healthy length. “It gets to the root cause of ageing in cells, not just treating the symptoms.

anti-agingDelay in Cellular Senescence

The powder extends cell life and slows down tissue deterioration due to ageing. Topical and oral treatments translate into improved skin elasticity, reduced production of wrinkles and increased ability for tissue regeneration.

Cell Activation and Repair

The tetrapeptide sequence initiates cellular repair pathways, which improves mitochondrial function and protein synthesis. This dual effect lends support to preventative and reparative anti-aging techniques in product compositions.

Circadian Rhythm Control

Research has shown the benefits of normalising the production pattern of melatonin which could promote the quality of sleep . This puts the substance in the sleep support and health supplement categories.

Antioxidant Characteristics

In addition to structural restoration, the chemical also demonstrates free radical scavenging ability which provides another line of defence against oxidative stress that accelerates ageing processes.

Application Scenarios Across Industries

High-End Skincare Formulations

The powder from luxury cosmetic manufacturers are serums, creams and essence treatments for older skin. In leave-on formulations, concentrations are typically between 0.5% and 2%, and obvious changes in skin texture and firmness are seen.

Dietary Supplement Manufacturing

Capsules or tablets that are lifespan supplements are a booming market. The stability of the Epitalon Powder makes it easy to include in your regular wellness regimen, typically alongside resveratrol or NAD+ precursors.

Anti-Aging Health Products

Higher dosages validated by clinical data are utilised in specialised formulations for age management regimens. These items cater to health-conscious consumers looking for science-based therapies.

Cell Repair Therapeutics

Research institutions and specialised healthcare providers are looking for applications in regenerative medicine, where cellular rejuvenation fits into broader therapeutic procedures.

Quality Assurance and Compliance

We manufacture in a GMP regulated facility with many quality control checkpoints. Each batch is tested to the fullest extent with HPLC purity confirmation, heavy metal screening and microbiological testing. The testing protocols follow USP and EP pharmacopeial standards.

We provide entire paperwork packages including Certificate of Analysis (COA), Technical Data Sheet (TDS), Allergen Statement, Non-GMO Declaration and religious certifications (Halal, Kosher). Regulatory filing requirements are met with third party testing services available upon request.

Batch traceability systems provide complete supply chain visibility from the sourcing of raw materials to final packaging. This documentation assistance can benefit your product development and regulatory approval processes.

factory

Customization Services for Global Partners

Adjustment of Specification

Our normal product has a purity of ≥98.0%, but we can also meet the requirements for higher purity grades (99%+) for injectables and pharmaceutical applications. Custom particle size distribution available for individual formulation needs.

Packaging Solutions

In addition to the usual 25 kg fibre drums we can also supply the product in flexible packaging sizes of 1 kg, 5 kg and 10 kg. Your brand positioning is reinforced by custom printing and documentation from private labelling services.

Technical Assistance for Application

Our R&D staff is available to assist with formulation direction, stability testing suggestions and compatibility testing. This consultative method saves your formulation trial costs and accelerates your product development time frame.

Regulatory Information

We write unique documentation to meet your target market needs, be it FDA DMF, EU REACH registration or regional cosmetic ingredient registrations.​​​​​​​

Supply Chain Advantages

We provide controlled storage conditions to ensure your production plans are not disturbed with over 30 days of safety stock. We have a global logistics network with variable delivery options including EXW, FOB, CFR, CIF, DAP and DDP.

Payment flexibility: T/T, Western Union, PayPal, and Alibaba Trade Assurance to suit different company requirements. We show our operational excellence in order fulfilment with a 98% on-time delivery rate.

With many manufacturing lines, we're able to manufacture both standard and custom orders at the same time, so your custom needs won't delay delivery. This scalability is good for new brands as well as for existing organisations.

certification

Packaging and Storage

Standard packaging is 25 kg fibre drums with double layer food-grade polyethylene bag liners, which are crucial moisture barriers for the preservation of hygroscopic peptides. Desiccant packs keep moisture levels down during storage and shipment.

The product is stable when stored refrigerated at 2-8℃ for long term stability and when adequately sealed at controlled room temperature (below 25℃). Store in the dark, avoid several freeze/thaw cycles which could damage the peptide structure.

If you need to order in large quantities - above 500 kg, we organise special transportation in cold chain, with guarantyd temperature-controlled delivery from our factory to your warehouse.

FAQ

Q: Is Epitalon suitable for delicate skin use?

A: Sure. The tetrapeptide structure provides great dermatological tolerance with low irritation risk. Suitable for the sensitive skin and barrier weakened skin disorders. Our advice is to do normal patch testing before going into full formulation but clinical data shows these are skin friendly across a wide range of users.

Q: What are the stability considerations for aqueous formulations?

A: The powder is most stable at pH 5.0-7.0 which is consistent with formulation criteria for skin compatibility. Peptides are maintained in an intact form by a chelating agent and suitable preservation systems in aqueous systems. Keep away from strong oxidising chemicals and high temperatures during processing. For longer shelf life in liquid formulations, use airless packing to minimise oxidative deterioration.

Q: What is the difference between your product and lower purity products?

A: Our criterion of ≥98.0% purity guarantees maximum bioactivity with low contaminants, which could elicit unpleasant reactions. Advanced purification procedures remove synthesis by-products, residual solvents and degradation products. The therapeutic claims and premium positioning of the product are supported by the pharmaceutical-grade quality, which justifies higher price points in competitive markets.

Q: Is the powder suitable for liposomal delivery systems?

A: For sure. The tetrapeptide is hydrophilic, yet it is efficiently encapsulated in the aqueous core of liposomes, which improves its skin penetration and absorption. This is especially useful for topical applications where penetration into the deeper layers of the skin is important for efficacy. Our technical staff can give compatibility data for commonly used phospholipid systems in the manufacture of cosmetic liposomes.

Q: What causes the occasional colour differences between batches?

A: Batches of high purity (≥98.0%) always exhibit a white crystalline powder. A slight off-white colour may be due to trace peptide fragments which are within acceptable limits of purity. All lots that fulfil our specifications show equivalent activity in biological assays. When colour consistency is crucial in applications, we provide high-grade material with advanced filtering methods.team

Contact Us for Partnership Opportunities

Ready to integrate pharmaceutical-grade Epitalon Powder into your product line? Request samples, technical documentation, or quotations by contacting enquiry@lenutra.com.

Online Message