Ergothioneine Powder
Specification: 98%, 99% (HPLC) Source: Extracted from edible mushrooms or produced via bio-fermentation, purified via chromatographic separation Molecular Formula: C₉H₁₅N₃O₂S Application: High-end anti-aging cosmetics, skin repair products, dietary supplements, antioxidant formulations, pharmaceutical intermediates, food additives, biochemical research reagents Function: Powerful long-acting antioxidant;skin brightening;barrier repair;melanin inhibition Packaging: 25 kg fiber drum, lined with double-layer food-grade polyethylene bags Certificates: COA, TDS, Allergen, Non-GMO, Halal, Kosher, ISO, GMP. Delivery Terms: EXW, FOB, CFR, CIF, DAP, DDP Payment Method: T/T, Western Union, Pay Pal, Alibaba Assurance Account 10 years experience on natural ingredients industry.
Description
Ergothioneine Powder – Premium Anti-Aging Ingredient with Superior Stability and Bioavailability
Xi'an Le-Nutra Ingredients Inc produces pharmaceutical grade Ergothioneine Powder, with purity up to 98% ~ 99% (by HPLC). Our product is manufactured using modern bio-fermentation and chromatographic purification techniques in our 60,000㎡ GMP-certified production facility, offering excellent thermostability (up to 120°C), broad pH tolerance (3.0–9.0), and optimal water solubility (>0.9 g/mL). We have a yearly production capacity of 3,000 tonnes with a skilled R&D staff for tight quality control, providing consistent batch quality, full traceability, and 98% on-time delivery worldwide for nutraceutical, cosmetic and pharmaceutical applications.

What Makes Ergothioneine Powder a Superior Antioxidant?
The substance has a specific chemical framework and biological uptake process, which separates it from classical antioxidants. It is a derivative of an amino acid containing sulphur. At physiological pH it resides in the stable thione state and does not have the problems of autoxidation that are characteristic of classical thiols such as glutathione.
The formulas exploit the dedicated OCTN-1 transporter protein to your advantage. This specialised carrier actively concentrates the chemical in tissues with high oxidative stress including skin, liver and ocular tissues. This active transport mechanism, unlike passive diffusion-reliant antioxidants, enables precise delivery to the sites where protection is most required.
The crystalline white to off-white powder is active under manufacturing circumstances which destroy vitamin C or vitamin E. It is suited for complex production conditions in the cosmetics and dietary supplements industries due to its tolerance to heat processing and pH changes.
Technical Specifications and Quality Parameters
| Parameter | Specification |
|---|---|
| Product Name | Ergothioneine (L-Ergothioneine, EGT) |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥98%, 99% |
| Loss on Drying | ≤2.0% |
| Heavy Metals | ≤10 ppm |
| Lead (Pb) | ≤0.5 ppm |
| Arsenic (As) | ≤1.0 ppm |
| Cadmium (Cd) | ≤0.5 ppm |
| Mercury (Hg) | ≤0.1 ppm |
| Total Plate Count | ≤1000 CFU/g |
| Yeast & Mold | ≤100 CFU/g |
| E. Coli | Negative |
| Salmonella | Negative |
| Molecular Formula | C₉H₁₅N₃O₂S |
| CAS Number | 497-30-3 |
| Storage Conditions | Sealed, cool, dry, protected from light and high temperature |
| Shelf Life | 24 months |
Multi-Functional Benefits for Advanced Formulations
Ergothioneine Powder's full bioactive profile gives your product development great competitive benefits. The chemical acts as a long-acting antioxidant with action duration substantially longer than standard alternatives.
Skin Repair & Protection
It protects cell structures from UV damage and helps the skin’s natural barrier function. The substance works by blocking the pathways of melanin synthesis, which means lightening effects without the harsh chemical bleaching.

Anti Ageing Mechanisms
It addresses the underlying ageing processes at the cellular level, neutralising reactive oxygen species and protecting mitochondrial function. Your formulas have apparent results on the reduction of fine lines and skin texture improvement.

Soothing Qualities
It inhibits inflammatory responses and so is a helpful ingredient in post-procedure recovery products and sensitive skin care lines.
Industrial Applications Across Multiple Sectors
High End Cosmetics & Personal Care
Its durability in water-based formulas makes it ideal for high-end anti-aging serums, eye creams, and luxurious skin care systems. Your products are stable over the shelf life and do not require complex stabilisation systems.
Dietary Supplements / Nutraceuticals
Its bioavailable form is utilised in antioxidant support goods, longevity supplements and cognitive health products. The specific transporter allows efficient absorption and tissue dispersion.
Pharmaceutical Intermediates
We reliably provide purity levels required for research grade neuroprotection investigations and oxidative stress management techniques.
Sun Care & UV Protection
It is found in post-sun healing treatments and daily UV defence formulas as a supplemental active ingredient to the standard sunscreen filters.

Production Excellence and Quality Assurance
We use a bio-fermentation production process to guarantee stereochemical purity of 100% L-isomer content. The exact production eliminates the imperfections inherent in chemical synthesis or crude natural extraction.
Six multifunctional production lines with chromatographic separation systems are now working on raw materials in controlled settings. Each batch is rigorously tested using modern HPLC analytical procedures before release.
Third party verification that EU cosmetic rules, FDA food additive standards and international pharmaceutical standards are met. All shipments are accompanied by full documentation including COA, TDS, allergies declarations and non-GMO certification.
Our quality control laboratory does heavy metal screening, microbiological testing and stability analysis. You have consistent material specs on each order with more than 30 days of safety stock.

Packaging and Global Delivery
Standard packaging 25 kg fibre drums with double layer food grade polyethylene liners. This setup safeguards against moisture, light, and contamination during overseas shipping.
We accept various delivery terms, such as EXW, FOB, CFR, CIF, DAP, and DDP. We have strategic logistical agreements that mean we can offer trusted marine freight, air cargo and fast courier services to worldwide destinations.
Payment flexibility: T/T bank transfer, Western Union, PayPal, Alibaba Trade Assurance for secure transactions.
FAQ
Q: What distinguishes ergothioneine from other antioxidants?
A: Unlike vitamin C or vitamin E, which are passively diffused, ergothioneine is actively taken up by a particular cellular transporter (OCTN-1). This process allows accumulation in tissues under high stress and provide a more prolonged protection.
Q: What purity levels do you have?
A: We have two pharmaceutical grade requirements 98% and 99% purity using HPLC. Both are compliant with international regulations for use in nutritional supplements and cosmetics.
Q: How stable is the substance in formulations?
A: Yeah. The thione tautomer exists in a surprisingly stable form in the pH range of 3.0-9.0 and at temperatures up to 120°C. This thermal resistance is consistent with typical manufacturing techniques.
Q: Is this compatible with other active ingredients?
A: Research has indicated that there are synergistic effects with other antioxidants. It improves the effectiveness of preparations containing derivatives of ascorbic acid, tocopherols and peptide complexes.
Q: What's the minimum order quantity?
A: We have flexible MOQ choices for R&D sampling and commercial scale production. Please contact our team to discuss your unique volume needs.
Q: Do you have any documents demonstrating your compliance with regulations?
A: Regulatory support packages are fully available and include batch-specific Certificates of Analysis, Safety Data Sheets, Allergen Declarations and Non-GMO documentation. We help with the registration requirements in your target markets.

Partner with a Reliable Ingredient Supplier
Ready to elevate your product line with Ergothioneine Powder? Contact our team at enquiry@lenutra.com for samples, technical specifications, and customized quotations tailored to your production needs.
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