Salicylic Acid Powder
Description
Salicylic Acid Powder – Professional Keratolytic Ingredient for Cosmetic & Pharmaceutical Applications
Xi'an Le-Nutra Ingredients Inc is a professional manufacturer of pharmaceutical grade Salicylic Acid Powder with assay purity 99.0%-100.5%, and has more than 14 years' experience in functional ingredient manufacturing. We process 3,000 tonnes a year in a 60,000㎡ GMP-compliant facility with 6 multipurpose lines, guaranteeing a consistent supply to global cosmetic, pharmaceutical and personal care firms. This keratolytic agent is CP compliant and has full testing data available enabling formulation creation for acne treatment, exfoliating serums and anti-dandruff products.
Technical Specifications & Quality Parameters
Our product undergoes comprehensive analytical testing to assure pharmaceutical-grade consistency for B2B use.
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White crystalline powder | Visual inspection |
| Assay (C7H6O3) | 99.0%-100.5% | HPLC |
| Loss on Drying | ≤0.5% | Gravimetric |
| Melting Point | 158-161℃ | Capillary method |
| Chloride Content | ≤100 ppm | Ion chromatography |
| Sulfate Content | ≤200 ppm | Turbidimetric |
| Heavy Metals | ≤20 ppm | ICP-MS |
| Residue on Ignition | ≤0.1% | Muffle furnace |
The product conforms to Chinese Pharmacopoeia standards with 24-month shelf life when stored in cool, dry conditions away from direct sunlight.
Four Core Functional Mechanisms
Keratolytic Exfoliation
The β-hydroxy structure allows penetration of lipid-soluble substances into sebaceous follicles, dissolving intercellular lipids in the stratum corneum. At 0.5%-2% concentration it stimulates desquamation without mechanical abrasion, making it well-suited for chemical peel compositions.
Anti-Acne & Oil Control
It brings the sebaceous glands back to normal by regulating the turnover of keratinocytes and minimising comedogenic obstructions. Clinical formulations are most effective against colonisation of Propionibacterium acnes at pH 3.0-4.0.
Technology for Pore Decongestion
Its small size (138 Da) and lipophilic nature allow deep follicular penetration, removing oxidised sebum and cellular debris that induce blackhead production. This process is distinct from that of surface-acting alpha-hydroxy acids.
Cuticle Conditioning Properties
In hair care applications, Salicylic Acid Powder removes scalp buildup and regulates dandruff by normalizing keratinocyte differentiation. Shampoo formulations usually include a concentration of 1.8%–3.0% for therapeutic efficacy.
Wide-Spectrum Application Scenarios
Acne Treatment Systems
Used in leave-on serums, spot treatments and medicated cleansers for inflammatory acne vulgaris. Our powder is compatible with niacinamide and retinoids in professional lines.
Blackhead & Deep Cleansing Treatment
Used as the main active in pore-refining masks, clay-based cleansers and pre-peel preparations. The chemical is more soluble in oil than in glycollic acid and is more effective on comedones.
Solution for Chemical Peel
Superficial Peel operations done by professional aestheticians are done with 20%-30% concentrations. Pharmaceutical-grade purity ensures reliable depth control and minimises the possibility of post-inflammatory hyperpigmentation.
Body Care Formulary
Treatments for keratosis pilaris, exfoliating creams for feet and lotions to prevent ingrown hair. The powder is distributed evenly in emulsion systems without crystallisation problem.
Scalp Therapy Products
For seborrhoeic dermatitis and psoriasis used in medicated shampoos and scalp tonics. Formulations balance keratolytic action with conditioning ingredients to prevent over-drying.
Advanced Customization & Formulation Support
Our technical staff can provide complete OEM/ODM services for brands that need customised solutions. We tailor the particle size distribution (D50: 20-80 μm) according to the specific needs for dispersion in anhydrous gels or aqueous solutions.
For compound formulae, we offer synergistic combinations of the product with complimentary actives such as azelaic acid, zinc PCA or tea tree oil. Pilot testing optimise pH buffering systems and solubilising agents for stability during 18-month accelerated ageing tests.
Private label services include unique packaging options from 1kg laboratory samples to 25kg fibre drums with nitrogen flushing for prolonged shelf life. All batches are supplied with a COA, TDS, allergies declarations and regulatory compliance papers for target markets.
Quality Assurance & Global Compliance
We confirm HPLC in our QC laboratory with the use of USP-grade reference standards with spectrophotometric confirmation at 296 nm. Batch to batch traceability links raw material sourcing to final product release and supports FDA Drug Master File submissions and EU CosIng compliance.
Heavy metal screening (As, Pb, Cd, Hg) validated through third-party testing partnerships, microbiological limitations (TPC <1000 cfu/g), and pesticide residue analysis. We are ISO 9001:2015 and GMP certified with annual audits, continually validating processes to pharmaceutical and cosmetic production standards.

Flexible Global Supply Solutions
We provide flexible MOQ for trial orders from 25kg and have over 30 days safety stock reserves to cater for seasonal demand fluctuation. Multi-modal logistics options, EXW, FOB Qingdao/Shanghai, CIF major ports, DDP to EU/US warehouses.
Payment terms: T/T, Paypal, Western Union, Alibaba Trade Assurance for transaction security. Express air freight (DHL/FedEx) samples 1-5 kg in 5-7 days, and aggregated marine shipments make the most sense for big orders above 500 kg.

Packaging & Storage Recommendations
Standard packaging is 25 kg fibre drums with double layer food grade polyethylene liners, nitrogen displacement to minimise oxidation. Smaller quantities (1 kg, 5 kg) are offered in heat sealed packs of aluminium foil together with desiccant bags.
Store in cool places below 25 °C and relative humidity below 60%. Close the containers tightly after each usage to prevent moisture absorption that can lead to caking. Properly kept material retains specification compliance for 24 months from date of manufacture.
FAQ
Q: How is the product different than capryloyl salicylic acid in formulation?
A: Regular salicylic acid has a direct keratolytic effect and is more potent, but might irritate sensitive skin if the concentration is >2%. The enzymatic release is slow, providing a milder exfoliation, which is perfect for everyday products, capryloyl salicylic acid. Your formulation goals will define the best choice – our technical staff can suggest concentration ranges based on target skin types.
Q: What stabilisation methods prevent deterioration in aqueous formulations?
A: The phenolic hydroxyl group is easily oxidised and light-sensitive. We recommend pH correction to 3.5-4.0 with citric acid buffers, addition of antioxidants such as sodium metabisulfite (0.1%) and storage in amber glass or opaque PET containers. Anhydrous formulations with silicone bases remove any dangers of hydrolysis.
Q: Can this ingredient be combined with retinoids or AHAs?
A: Yes, but the protocols you layer matter. In co-formulation pH above 3.2 to avoid significant irritation. Or, propose a rotation of application schedules to your end users (AM/PM rotation). Our formulation lab conducts compatibility testing to ensure synergistic stability for complicated active systems.
Q: What is the typical dissolution process in cold-process cosmetic manufacturing?
A: The powder quickly dissolves in ethanol, propylene glycol, or hot water (>60°C). For room temperature procedure, pre-dissolve in a glycol phase before to adding to the main emulsion. Do not add directly to high pH bases (>6.0) to avoid salt production which will decrease bioavailability.
Q: Do you give regulatory support across markets?
A: We provide all papers like IFRA compliance statements, California Prop 65 declarations and REACH pre-registration numbers. We also have maximum usage levels for cosmetic applications (2% FDA OTC monograph, 0.5% EU Cosmetics Regulation for leave-on products) as per regional requirements in our dossiers.

Contact Us for Technical Consultation
Ready to integrate premium Salicylic Acid Powder into your product line? Request COA, customized quotations, or technical data sheets by contacting enquiry@lenutra.com.
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