Knotweed Extract

Knotweed Extract Powder – High-Purity Resveratrol Source for Nutraceuticals, Functional Foods & Advanced Cosmetics

Xi’an Le-Nutra Ingredients Inc. offers pharmaceutical-grade Knotweed Extract, sourced from certified Polygonum cuspidatum roots, standardised to 98% trans-resveratrol, validated by HPLC. Our 60,000㎡ GMP-compliant facility processes 3,000 tonnes annually using controlled extraction techniques, producing off-white crystalline powder with heavy metals below 2 ppm and microbiological counts under 1000 CFU/g. With 14+ years of botanical extraction experience and 98% on-time global delivery, we give batch-traceable, ISO-certified resveratrol solutions to nutraceutical manufacturers, cosmetic formulators, and functional food producers across 40+ countries.

What Makes Our Knotweed Extract Superior?

The Japanese knotweed roots are a source of natural polyphenols which are purified through a multistage process, resulting in a final product with 98% purity of trans-resveratrol. The crystalline structure improves bioavailability relative to crude extracts and is stable in pH 3-8 formulations.

Our closed loop extraction technology enables preservation of heat sensitive polyphenols by temperature regulated processing. Clinical-grade supplements require constant batch-to-batch active ingredient ratios, confirmed by independent third-party testing, which is critical for dose accuracy.

The raw material is screened in 2 layers: Pesticide residue testing according to EU regulation 396/2005 and Aflatoxins below 2 ppb. This pharmaceutical grade technique is appropriate for situations requiring stringent regulatory verification.

Technical Specifications & Quality Parameters

Core Functional Benefits for Product Formulation

Trans-resveratrol has been shown to affect numerous physiological pathways. In dermatology, activation of the SIRT1 gene in anti-aging pathways is associated with cellular lifespan.

It promotes good endothelial functions which are favourable for cardiovascular formulations. In supplement programs, the compound's antioxidant ability is able to neutralise free radicals at dosages as low as 50 mg daily.

Research suggests immune-modulating characteristics through NF-κB pathway control. This allows the Knotweed Extract to be used as a functional food for the treatment of inflammatory response.

In cosmetic grade uses such as anti-wrinkle serums, its photoprotective properties are exploited. The crystalline structure allows homogeneous dispersion in emulsion systems without degradation at normal manufacturing temperatures to 80°C.

Diverse Application Scenarios

Dietary Supplements: Capsules and tablets standardised to 50-500 mg trans-resveratrol per serving for longevity support formulas.

Functional Beverages: Water dispersible grades for ready to drink antioxidant drinks, stable throughout HTST pasteurisation.

Cosmetic Formulations: Anti-aging creams and serums with 0.5-2% concentration compatible with glycerin and hyaluronic acid delivery methods.

Pet Nutrition: Vet quality senior pet vitamins, oxidative stress in ageing pets.

Manufacturing Excellence & Quality Assurance

We have six multipurpose manufacturing lines using supercritical CO2 and ethanol extraction technologies optimised for the yield of resveratrol. Real-time HPLC monitoring during processing assures consistency with specifications before packaging.

All production batches are subjected to 17-point quality inspection including identification testing by HPTLC fingerprinting, residual solvent analysis as per USP <467> and allergy screening. The COA documentation includes particle size distribution and bulk density values, which are crucial for tableting applications.

The plant is FDA registered and is inspected annually for GMP. Temperature-controlled warehouses maintain product integrity from synthesis to transportation. 30 days of safety stock ensures continuous supply.

Custom Solutions & Direct Factory Advantages

Our customisation possibilities are driven by your formulation requirements. Depending on the application, whether it's cosmetic-grade or pharmaceutical-grade criteria, we tailor the resveratrol content from 50% to 99% purity levels.

We provide private label services, including custom packaging from 1 kg foil bags to 25 kg fibre drums with your branding. Our R&D team collaborates to optimise recipe, improve solubility and verify stability under your intended storage conditions.

Direct factory price removes distributor markups and maintains strict quality requirements. Flexible MOQ choices cater to trial batches for product development and bulk orders of over 500 kg for commercial production.

Packaging & Global Delivery Options

Standard packaging is 25 kg pharmaceutical grade fibre drums, with double layer food grade polyethylene liners and moisture barrier closures. Tailor-made packaging from 1 kg aluminium foil packets to 500 kg intermediate bulk containers.

We cooperate with international logistic companies and can supply EXW, FOB, CFR, CIF, DAP and DDP terms. Samples are sent by express shipping and delivered worldwide in 5-7 days. Bulk orders are shipped via sea freight with complete tracking and temperature monitoring.

Payment terms: 100% T/T transfer, Alibaba Trade Assurance protection , Western Union for first order. Our logistics staff handles all documents, including commercial invoices, packing lists and certificates of origin, to facilitate smooth customs processing.

FAQ

Q: How does your product compare to synthetic resveratrol?

A: Our botanical extract is composed of naturally occurring isomers of cis- and trans-resveratrol, as well as synergistic polyphenols including emodin, for increased bioactivity compared to isolated synthetic chemicals. HPLC chromatograms confirm complete phytochemical profiling.

Q: Will this extract survive the heat of encapsulation during manufacturing?

A: Trans-resveratrol is stable up to 120°C during short time processing. Enteric coating is recommended for formulations that are to be protected from gastric acid to optimise intestinal absorption.

Q: What documentation confirms compliance with export regulations?

A: All shipments are shipped with the FDA registration confirmation, ISO 22000 certification, Kosher certificate, complete COA with testing data, MSDS safety sheets and phytosanitary certificates for customs clearance in 50+ countries.

Q: How do you control pesticide contamination from wild-harvested roots?

A: We source exclusively from certified organic cultivation bases under contract farming agreements. Multi-residue screening tests for 200+ pesticides per EU standards, with results documented in batch-specific testing reports.

Q: What is the recommended dosage for cardiovascular health claims?

A: Clinical efficacy studies support 100-500 mg trans-resveratrol daily. Your product's specific dosage should align with regional health claim regulations and target demographic needs, which our technical team can assist in determining.

Partner With a Trusted Knotweed Extract Manufacturer

Contact our global supply team at enquiry@lenutra.com to discuss your Knotweed Extract project requirements and receive customized solutions within 24 hours.