Iohexol Powder

Iohexol Powder – Premium Non-Ionic Contrast Media API for Advanced Diagnostic Imaging Solutions

Xi'an Le-Nutra Ingredients Inc. offers pharmaceutical quality Iohexol Powder with purity ≥99%. With GMP certified workshop of 60,000㎡ and yearly capacity of 3,000 tonnes. This non-ionic contrast medium API has a defined molecular weight of 821.14 g/mol and an outstanding iodine concentration of 46.4% which provide excellent radiopacity for angiography, urography, myelography and CT-enhanced scanning. We have over 14 years of experience in the business. We offer 98% on-time delivery and full compliance documents such as COA, TDS, MSDS and HPLC chromatograms.

Understanding the Pharmaceutical Profile

This white to off-white crystalline powder is the basic raw material for most global non-ionic contrast agents. It is a revolutionary diagnostic imaging technology CAS number 66108-95-0 Molecular formula C₁₉H₂₆I₃N₃O₉

It is very soluble in water and hence easy to formulate for fast preparation before use. Because of its low osmolality and low molecular toxicity, it produces less adverse reactions than the conventional ionic alternatives.

We sell directly from the factory, so there are no markups, and we maintain tight quality controls throughout our extraction, crystallisation and packing processes. This vertical integration allows for the batch-to-batch consistency that is necessary for pharmaceutical manufacture.

Technical Specifications

Clinical Application Portfolio

Intravascular Diagnostics: High iodine density delivers excellent contrast enhancement in cardiovascular angiography, brain imaging and peripheral arteriography. The chemical is employed by medical personnel to precisely visualise the architecture of blood vessels.

Subarachnoid Uses: The special flow properties and tissue compatibility are used in special myelography and CT cisternography methods. Low osmolality minimises the discomfort patients feel when undergoing spine MRI treatments.

Body Cavity Examinations: The broad solubility profile lends itself to a broad spectrum of diagnostic techniques, from arthrography to endoscopic retrograde cholangiopancreatography (ERCP). High clearance rates are advantageous in urography and hysterosalpingography.

Research Use: Laboratory grade material is used as a density gradient medium in research for separation of cells and subcellular organelles. It is non-ionic and does not interfere with biological systems in centrifugation processes.

Manufacturing Excellence and Quality Assurance

Our versatile production lines incorporate innovative crystallisation equipment and precision drying technologies. Six dedicated processing units maintain pharmaceutical grade environmental controls that fulfil GMP, ISO and FDA compliance standards.

Quality control personnel rigorously test every production step. The purity level is checked by HPLC analysis, and the precision of iodine concentration is confirmed by atomic absorption spectroscopy. Heavy metal screening and microbiological testing is done according to international pharmacopoeia norms.

For large-scale pharmaceutical producers, we have more than 30 days of safety stock in several batch processes to ensure supply continuity. Each order is supplied with specific batch traceability documents to suit your regulatory submission needs.

Logistics and Packaging Solutions

Standard pharmaceutical packaging for commercial size orders comes in 25kg fibre drums with moisture-barrier liners. Research and development volumes are provided in aluminium foil bags, 1kg, 5kg and 10kg, nitrogen flushed.

The chemical is hygroscopic and should be stored at room temperature in dark sealed containers. Stability is maintained with proper handling during the 24–36 month shelf life range.

We have a global logistics network offering reliable marine freight, air cargo and express courier services to North America, Europe and Southeast Asia. We can provide adjustable MOQ according to your project scale.

Customization and Technical Support

Our OEM/ODM services are not limited to standard standards, but include unique purity grades, particle size distribution optimisation, special package configurations and much more. Formula development assistance for incorporating Iohexol Powder into your own contrast media formulas.

Our R&D team can assist with pre-formulation consultancy, stability testing methodologies and regulatory documentation. Technical experts are ready to help you with method transfer, process validation and troubleshooting throughout your product development cycle.

Multilingual customer support seamlessly handles sample requests, analytical certificate enquiries and shipment coordination. We focus on fast response times so that your project stays on schedule.

FAQ

Q: What advantages does iohexol have over ionic contrast agents?

A: Iohexol is a non-ionic contrast agent with advantages of low osmolality, lower inherent molecular toxicity and a much lower incidence of adverse effects. These qualities enhance the safety profile of the patient with superior diagnostic image quality.

Q: What is the long term storage stability of the powder?

A: When stored in the sealed container in dark, dry circumstances at room temperature, the crystalline structure is stable for 24-36 months. Loss on drying is specified as ≤0.5%, which suggests good moisture resistance with suitable handling techniques.

Q: Do you give lesser quantities for research use?

A: Yes, we have flexible packaging solutions starting from 1kg aluminium foil bags intended for R&D purposes. These volumes include full analytical documentation to facilitate laboratory-scale development of formulations.

Q: What documentation supports regulatory submissions?

A: Each batch comes with a Certificate of Analysis (COA), Technical Data Sheet (TDS), Material Safety Data Sheet (MSDS) and HPLC Chromatogram. Additional 3rd Party testing reports can be coordinated to suit specific regulatory needs in a variety of markets.

Q: How does the 46.4% iodine concentration improve image quality?

A: High theoretical iodine content provides excellent radiopacity, which immediately results in increased contrast in the X-ray image. This allows for better visualisation of anatomical structures at smaller dosage volumes, hence increasing diagnostic accuracy and patient comfort.

Contact Us for Your Contrast Media Requirements

Ready to secure pharmaceutical-grade material for your next production cycle? Reach out to enquiry@lenutra.com today for Iohexol Powder technical consultation and competitive pricing tailored to your order volume.