Indole-3-Carbinol Powder

Indole-3-Carbinol Powder – High-Purity Pharmaceutical Intermediate and Estrogen Metabolism Modulator for Dietary Supplements and Nutraceutical Applications

Xi'an Le-Nutra Ingredients Inc. is a professional manufacturer of high quality Indole-3-Carbinol Powder ≥99% (HPLC) for pharmaceutical intermediates, nutraceuticals and functional food applications. With our GMP-compliant production plant of over 60,000㎡ and an annual production capacity of 3,000 tonnes, we can guarantee constant quality and comprehensive batch traceability. Our product (CAS 700-06-1) utilises the latest crystallisation and purification processes to remove contaminants while maintaining molecular stability. With over 14 years of experience in natural compound extraction and strict compliance to ISO, FDA and Halal/Kosher certifications we provide reliable raw material solutions for world-wide manufactures of oestrogen metabolism modulators, aryl hydrocarbon receptor (AhR) agonists and chemopreventive ingredients.

What is Indole-3-Carbinol Powder?

The product is a high purity crystalline phytochemical substance isolated and standardised from cruciferous vegetables for use in commercial and research applications. 3-Indolemethanol, also known as 3-Hydroxymethylindole. A bioactive chemical, a powerful aryl hydrocarbon receptor (AhR) agonist, and an oestrogen metabolism regulator.

The powder form tackles major B2B hurdles, including handling issues with volatile substances, inconsistency in dosing with liquid formulations, and degradation concerns during storage. The substance is manufactured using regulated crystallisation techniques to preserve the molecular integrity and enhance the flowability for capsule filling, tablet compression, and accurate dosage in clinical research protocols.

This pharmaceutical grade chemical is a versatile building block for anti-cancer drug research, hormone-balancing supplements, and neuroprotective formulations targeting women's health markets and immunity improvement applications.

Product Specifications

Multi-Functional Mechanisms of Action

The chemical is an agonist of the aryl hydrocarbon receptor (AhR) and activates cellular defence pathways involved in xenobiotic metabolism and stimulation of detoxification enzymes. The chemopreventive qualities are mediated via modification of Phase I and Phase II enzyme systems that assist cellular defence mechanisms.

The role of modulating oestrogen metabolism is to divert oestrogen degradation to protective metabolites, rather than potentially damaging pathways. This mechanism makes it particularly useful in women's health formulations aimed at hormonal balance.

Antioxidant activity neutralises reactive oxygen species by different mechanisms. The neuroprotective benefits include support for mitochondrial activity and decrease of oxidative stress in cerebral tissues, enabling potential in cognitive health products.

These multi-target mechanisms together with other anti-cancer and antioxidant compounds increase the efficacy of the formulation and expand the opportunity for market positioning.

Diverse Application Scenarios

It is an important step in pharmaceutical development for the synthesis of anti-tumor drugs and the creation of oestrogen metabolism regulators. It is used as a tool chemical for AhR pathway studies and investigation of cancer preventing mechanisms in research institutions.

For dietary supplement makers it permits the creation of anti-cancer support capsules, female hormone balance products, liver protection supplements and immune function boosting formulae. The high purity level ensures consistent dosing in batch production cycles.

It is being added by functional food makers to fortified drinks, nutrition bars and wellness powders marketed to women worried about their hormone health. The small particle size permits homogeneous dispersion in dry-blend formulations without the problems of clumping or segregation.

It is employed in cosmetics for its antioxidant effects in anti-aging skincare products. The main demand is in the nutraceutical and pharmaceutical industries.

Comprehensive Quality Assurance System

All Indole-3-Carbinol Powder production batches are tested for purity by rigorous HPLC methods proving ≥99% active content and are fully documented with Certificate of Analysis (COA), Technical Data Sheet (TDS), Material Safety Data Sheet (MSDS) and thorough HPLC chromatogram. Our GMP production workshop is standardised for cleanroom conditions in the manufacturing process.

Full batch traceability systems track raw material sourcing to final packaging. Reference samples are kept for 12 months after production in accordance with sample retention guidelines, and can be used to support customer reinspection requests and quality verifications at any time.

Halal and Kosher certification can provide access to new markets for a range of consumer groups. Third-party testing help for conformity with regional requirements for North America, Europe and Southeast Asia markets. Our skilled QC team undertakes heavy metal screening, microbiological testing and residual solvent analysis to a higher quality than the industry norm.

Flexible Packaging and Storage Solutions

Standard packaging is 25kg fibre drums with double-layer food-grade polyethylene bag lining for cost-efficient shipping for bulk orders. We offer 1kg, 5kg and 10kg Aluminium foil bags for trial orders & small scale production testing that preserve product integrity during assessment phases.

Store in a cool, dry place away from light. Keep containers unopened. When stored long term at 2-8°C the shelf life is 24 months and maximum efficacy is retained throughout. Under optimal conditions, the crystalline structure is stable, lowering the risk of warehousing and distribution degradation.

Our global logistics network allows us to offer numerous delivery options. Large volume orders can be shipped by sea freight, urgent orders can be shipped by air and sample shipments can be shipped using expedited services. This will ensure your production schedules stay on track.

FAQ

Q: What makes the product suitable for women's health formulations?

A: This chemical is perfect for hormone balancing supplements since it may help promote oestrogen metabolism that favours the protective pathways. It helps break down oestrogen in a healthy way. This can be especially helpful for women who want natural ways to improve their hormone health. It also has antioxidants and may help protect cells.

Q: Is it possible to combine this component with other bioactive compounds?

A: Yes, the profile of the multi-target mechanism provides for outstanding interaction with other anti-cancer drugs, antioxidants and immune support elements. This synergy increases the total value of the product and allows formulators to develop holistic wellness solutions that can address many health pathways simultaneously.

Q: What documentation is needed for regulatory compliance in international markets?

A: We offer full batch records including COA, TDS, MSDS, HPLC chromatogram and Halal/Kosher certificates. Our manufacturing is GMP, ISO and FDA compliant with full traceability to enable regulatory submissions in many jurisdictions and streamline your compliance operations.

Q: What are the benefits of powder form to production efficiency compared to alternatives?

A: This crystalline powder flows well for automated capsule filling and tablet compression equipment, reduces worries of chemical volatility, and allows for accurate dosing uniformity. Fine particle size allows uniform dispersion in dry blends without specific handling equipment.

Q: What is the minimum order quantity you offer for test production runs?

A: We accommodate flexible MOQ starting from 1kg aluminum foil bag packaging for formulation testing and small-scale trials, scaling up to 25kg fiber drums for commercial production. This flexibility allows you to test product performance before investing in a larger inventory.

Partner with a Trusted Manufacturer

Ready to integrate pharmaceutical-grade Indole-3-Carbinol Powder into your next product line? Contact us today at enquiry@lenutra.com to request detailed specifications, pricing information, or arrange quality testing for your application needs.